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TranscriptomicsA systems approach identifies progeroid Ercc1[-/Δ] mice as a model system for kidney aging.
Using these samples, it has been shown that the transcriptional landscape in glomeruli of Ercc1[-/Δ] mice at a rather young age of 14 weeks mimics that of mice which have undergone real-life renal aging. Thus, young Ercc1[-/Δ] mice can be used as a model system for glomerular aging in future studies...
ORGANISM(S): Mus musculus 
2012-12-21 | E-GEOD-43061 | biostudies-arrayexpress
TranscriptomicsAltered lipid metabolism in the aging kidney identified by three layered omic analysis
Aging-related diseases and their comorbidities affect the life quality of a constantly growing proportion of our population. Age-associated changes of kidney structure and function are considerable contributors to the dramatically increased incidence of chronic kidney disease world-wide which has be...
ORGANISM(S): Mus musculus 
2015-10-30 | E-GEOD-74463 | biostudies-arrayexpress
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