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TranscriptomicsExpression Analysis of 17 human T-ALL cell lines
Using array CGH and fiber-FISH, we found that several human T-ALL have tandem duplication of the MYB gene on one allele, we used microarray gene expression analysis to determine if increased MYB expression correlates with gene duplication Keywords: cell type comparison RNA from 17 T-ALL cell lines
ORGANISM(S): Homo sapiens 
2007-10-19 | E-GEOD-9342 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Atm-/-,mTerc-/-,p53-/- triple knock-out lymphoma vs normal
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7607 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Atm-/-,mTerc-/-,p53-/- triple knock out lymphoma vs. normal mouse DNA (GPL2884)
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7600 | biostudies-arrayexpress
UnknownIntegrated genomic analyses of cutaneous T-cell lymphomas reveal the molecular bases for disease heterogeneity.
Not available
S-EPMC8499046 | biostudies-literature
GenomicsGenome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis

Monozygotic (MZ) twins have been widely employed for dissection of the relative contributions of genetics and environment in disease. In multiple sclerosis (MS), an autoimmune demyelinating disease that commonly causes neurodegeneration and disability in young adults, disease discordance in M...

phs000239.v2.p1 | EGA
TranscriptomicsComparative genomic hybridization (CGH) of human melanoma vs. normal human samples
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7606 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human colon tumor vs normal DNA
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7604 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human pancreatics tumors vs. normal tissue
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7599 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of human GBM tumor vs. normal human DNA induced in mice
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7602 | biostudies-arrayexpress
UnknownChronic cat allergen exposure induces a TH2 cell-dependent IgG4 response related to low sensitization.
Not available
S-EPMC4679456 | biostudies-literature
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