Sort   by:  
 Page size 
TranscriptomicsAKT antagonist AZD5363 influences estrogen receptor function in endocrine resistant breast cancer and synergizes with fulvestrant (ICI182780) in vivo
Phosphoinositide-3-kinase/protein-kinaseB/mammalian target of rapamycin (PI3K/AKT/mTOR) signalling plays an important role in breast cancer (BC). Its interaction with estrogen receptor (ER) signalling becomes more complex and inter-dependent with acquired endocrine resistance. Targeting mTOR combine...
ORGANISM(S): Homo sapiens 
2015-06-29 | E-GEOD-69893 | biostudies-arrayexpress
TranscriptomicsDifferences in the Transcriptional Response to Fulvestrant and Estrogen Deprivation in ER-Positive Breast Cancer
Aromatase inhibitors are first-line postmenopausal agents for estrogen receptor alpha (ERa)-positive breast cancer. However, there is considerable response heterogeneity and women frequently relapse. Estrogen deprivation does not completely arrest ERa activity, and transactivation of the unliganded ...
ORGANISM(S): Homo sapiens 
2015-08-07 | E-GEOD-71791 | biostudies-arrayexpress
GenomicsGAW16 Framingham and Simulated Data

Important links to apply for individual-level data

  1. Genetic Analysis Workshop
  2. Instructions to Request Authorized Access
phs000128.v3.p3 | EGA
Sort   by:  
 Page size