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TranscriptomicsBrain metastasis from lung adenocarcinoma patients
Microarray analysis of 28 brain metastasis samples from lung adenocarcinoma patients. 28 brain metastasis samples: 19 from Marc Ladanyi 9 from William L. Gerald
ORGANISM(S): Homo sapiens 
2010-06-17 | E-GEOD-14108 | biostudies-arrayexpress
TranscriptomicsMesothelioma tumor aCGH profiles
Malignant pleural mesotheliomas (MPMs) often show CDKN2A and NF2 inactivation but other highly recurrent mutations have not been described. To identify additional driver genes, we used an integrated genomic analysis of 53 MPM tumor samples to guide a focused sequencing effort that uncovered somatic ...
ORGANISM(S): Homo sapiens 
2011-09-25 | E-GEOD-29902 | biostudies-arrayexpress
TranscriptomicsEWS-WT1 Oncogene Activates a Neuronal Reprogramming Factor ASCL1 and Mediates Partial Neural Differentiation
A chromosomal translocation fusion gene product EWS-WT1 is the defining genetic event in Desmoplastic Small Round Cell Tumor (DSRCT), a rare but aggressive tumor with a high rate of mortality. EWS-WT1 oncogene acts as an aberrant transcription factor that drives tumorigenesis, but the mechanism by w...
ORGANISM(S): Mus musculus 
2014-09-11 | E-GEOD-53301 | biostudies-arrayexpress
TranscriptomicsExpression data from transfected BJ fibroblast cell line
Skeletal muscle differentiation is a highly coordinated multistep process in which proliferating mononucleated myoblasts ?rst withdraw from the cell cycle, then differentiate into postmitotic mononucleated myocytes, and subsequently fuse into multinucleated myotubes which ?nally bundle to form matur...
ORGANISM(S): Homo sapiens 
2014-05-01 | E-GEOD-56078 | biostudies-arrayexpress
TranscriptomicsExpression data from transfected C2C12 cell lines
Skeletal muscle differentiation is a highly coordinated multistep process in which proliferating mononucleated myoblasts first withdraw from the cell cycle, then differentiate into postmitotic mononucleated myocytes, and subsequently fuse into multinucleated myotubes which finally bundle to form matur...
ORGANISM(S): Mus musculus 
2014-05-01 | E-GEOD-56079 | biostudies-arrayexpress
TranscriptomicsaCGH data for mesothelioma cell lines
Malignant pleural mesotheliomas (MPMs) often show CDKN2A and NF2 inactivation but other highly recurrent mutations have not been described. To identify additional driver genes, we used an integrated genomic analysis of 53 MPM tumor samples to guide a focused sequencing effort that uncovered somatic ...
ORGANISM(S): Homo sapiens 
2011-05-19 | E-GEOD-29383 | biostudies-arrayexpress
TranscriptomicsThe nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma
This SuperSeries is composed of the following subset Series: GSE29354: Mesothelioma tumor gene expression profiles GSE29383: aCGH data for mesothelioma cell lines Refer to individual Series
ORGANISM(S): Homo sapiens 
2011-05-19 | E-GEOD-29211 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human embryonal rhabdomyosarcoma (EMRS) culture to identify PAX3-FKHR regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcomas
The overall goal and objective is to study the degree to which PAX3-FKHR accounts for differences between ARMS and ERMS by expressing a construct (termed P3FK/ER) consisting of PAX3-FKHR joined to the estrogen receptor ligand binding domain in an ERMS cell culture system. Experiment Overall Design: ...
ORGANISM(S): Homo sapiens 
2009-03-14 | E-GEOD-15103 | biostudies-arrayexpress
GenomicsWhole Genome and Exon Capture Sequencing of Bladder Cancers

One primary bladder cancer and paired peripheral blood sample were subjected to whole genome sequencing on an Illumina HiSeq 2000 platform. This technology was utilized to investigate the genetic basis of a durable remission of metastatic bladder cancer in a patient treated with everolimus, a dru...

phs000535.v1.p1 | EGA
GenomicsNational Human Genome Research Institute Tumor Sequencing Project (TSP) - Lung Adenocarcinoma

The Tumor Sequencing Project (TSP) Consortium is a collaboration among participants at the Baylor College of Medicine Human Genome Sequencing Center, the Broad Institute Genome Sequencing Platform, the Dana Farber Cancer Institute, the Memorial Sloan-Kettering Cancer Center, the Genome Seque...

phs000144.v1.p1 | EGA
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