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TranscriptomicsMouse Soleus Muscle Chronic Electrical Stimulation Study
Stimulation of the mouse hindlimb via the sciatic nerve was used to induce contractions for 4 hours to investigate acute muscle gene activation in a model of muscle phenotype conversion. Initial force production (1.6 + 0.1 g/g body weight) declined 45% within 10 min and was maintained for the remain...
ORGANISM(S): Mus musculus 
2010-06-01 | E-GEOD-14391 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP 6.0 data for analysis of esophageal adenocarcinoma samples
Esophageal adenocarcinoma is characterized by complex chromosomal alterations. Tumors were evaluated to identify regions of recurrent copy gains and losses and to determine the prognositic significance of the degree of segmental aneuploidy as measured by SNP array. 41 superficial esophageal adenocar...
ORGANISM(S): Homo sapiens 
2013-12-01 | E-GEOD-49396 | biostudies-arrayexpress
TranscriptomicsDistinct human stem cell populations in small and large intestine
The intestine is composed of an epithelial layer, containing rapidly proliferating cells that mature into two distinct anatomic regions, the small and the large intestine. Although previous studies have identified stem cells as the cell-of-origin for the whole intestine, no studies have compared ste...
ORGANISM(S): Homo sapiens 
2015-01-15 | E-GEOD-56525 | biostudies-arrayexpress
TranscriptomicsRenal Cell Neoplasms Contain Shared Tumor Type-Specific Copy Number Variations
Copy number variant (CNV) analysis was performed on renal cell carcinoma (RCC) specimens (chromophobe, clear cell, oncocytoma, papillary type 1, papillary type 2) using high resolution arrays (1.85 million probes). RCC samples exhibited diverse genomic changes within and across tumor types ranging f...
ORGANISM(S): Homo sapiens 
2012-04-28 | E-GEOD-34676 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Stratagene human universal reference RNA labelled with different labelling protocols to test labelling protocols
Considerable variation in gene expression data from different DNA microarray platforms has been demonstrated. However, no characterization of the source of variation arising from labeling protocols has been performed. To analyze the variation associated with T7-based RNA amplification/labeling metho...
ORGANISM(S): Homo sapiens 
2007-07-24 | E-GEOD-3254 | biostudies-arrayexpress
TranscriptomicsRegulation of dendritic cell genes by alpha fetoprotein
Human dendritic cells (DC) are suppressed by tumor-derived alpha fetoprotein (AFP), but less so by cord blood-derived normal AFP. We tested human DC from 5 healthy donors for transcriptional changes induced by tumor (tAFP) or cord blood (nAFP) AFP, vs. chicken ovalbumin (OVA) control.
ORGANISM(S): Homo sapiens 
2014-12-23 | E-GEOD-62005 | biostudies-arrayexpress
TranscriptomicsmiRNA Expression in 4 prostate cell types from human tumor biopsies
Prostate primary epithelial and stromal cells were isolated from normal donorhuman prostate tissue and patient prostate tumors (>Gleason 8) using in vitroselective media conditions and differential substrate adhesion properties.Tumor cells specific to the prostate epithelial cell component attached ...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-17321 | biostudies-arrayexpress
TranscriptomicsmiRNA expression of 3 prostate cell types from human normal donors
Prostate primary epithelial and stromal cells were isolated from normal donorhuman prostate tissue and patient prostate tumors (>Gleason 8) using in vitroselective media conditions and differential substrate adhesion properties.Tumor cells specific to the prostate epithelial cell component attached ...
ORGANISM(S): Homo sapiens 
2015-07-01 | E-GEOD-17323 | biostudies-arrayexpress
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