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UnknownThe nicotinic α6 subunit gene determines variability in chronic pain sensitivity via cross-inhibition of P2X2/3 receptors.
Not available
S-EPMC5018401 | biostudies-literature
TranscriptomicsExercise-associated changes of leukocyte gene expression in Stratin-associated myopathy - A case study
Biological Relevance and Intent of the Experiment Statin-associated muscle symptoms (SAMS) are among the most common adverse effects limiting the use of statin therapy, yet their underlying biological mechanisms remain poorly defined. While metabolic and structural causes have been proposed, increas...
ORGANISM(S): Homo sapiens 
2025-11-13 | E-MTAB-15840 | biostudies-arrayexpress
TranscriptomicsKLF13 regulate memory-like CD8 T cells
“Memory-like T cells” are a subset of thymic cells that acquire effector function through the maturation process rather than interaction with specific antigen. Disruption of genes encoding T cell signaling proteins or transcription factors have provided insights into the differentiation of such cell...
ORGANISM(S): Mus musculus 
2010-11-23 | E-GEOD-25502 | biostudies-arrayexpress
UnknownLinked electronic health records for research on a nationwide cohort of more than 54 million people in England: data resource.
Not available
S-EPMC8413899 | biostudies-literature
UnknownClinical academic research in the time of Corona: A simulation study in England and a call for action.
Not available
S-EPMC7425844 | biostudies-literature
ProteomicsOptimization of Proteomics Sample Preparation for Forensic Analysis of Skin Samples
We present an efficient protein extraction and in-solution enzymatic digestion protocol optimized for mass spectrometry-based proteomics studies of human skin samples.
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD022720 | Pride
Proteomics  sample preparation  protein extraction  trypsin digestion  surfactants  human forensics 
GenomicsA sequence-based genetic dissection of human immune cell types and implications for immune-related disease.
The immune system is an intricate biological network mediating interactions with other organisms while preserving the integrity of our tissues. By mounting appropriate responses it protects us from a vast range of pathogens while inadvertent immune system attacks on self result in autoimmune disease...
EGAS00001000574 | EGA
GenomicsNational Institute on Aging (NIA) SardiNIA Study

Sardinia is the second largest island in the Mediterranean and constitutes a genetically isolated founder population. This population has aided in the identification of genes involved in several Mendelian disorders and is attractive for genetic studies due to its organization in long-establishe...

phs000338.v1.p1 | EGA
GenomicsSardiNIA Medical Sequencing Discovery Project

The SardiNIA Medical Sequencing Discovery Project is a study of the genetics of blood lipid levels and personality in a Sardinian population cohort. The project will generate draft genome sequences for 1,000 individuals using whole genome shotgun sequencing. The draft sequences will allow investi...

phs000313.v3.p2 | EGA
TranscriptomicsTranscriptome analysis of Dop1R2 RNAi in Drosophila melanogaster
The process of metamorphosis relies on choreography of temporal and spatial cues that mediate, in which inappropriate activation of many of these genes results in growth defects, developmental delay and death. Using RNA interference, we have unraveled an essential role for the insect specific dopam...
ORGANISM(S): Drosophila melanogaster 
2015-09-01 | E-GEOD-66496 | biostudies-arrayexpress
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