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TranscriptomicsSmall RNA deep sequencing of cellular subcompartments
RNA deep sequencing efforts have revealed abundant expression of small RNAs derived from small nucleolar (sno) RNAs. We employ here spatial RNA deep sequencing to assess the expression of 10-40 nt small RNAs in subcellular compartments of HeLa cells. Total cellular, cytoplasmic, nuclear and nucleola...
ORGANISM(S): Homo sapiens 
2014-05-07 | E-GEOD-50057 | biostudies-arrayexpress
TranscriptomicsProfiling of novel p53-inducing compounds
We describe six novel lead compounds activating the p53 tumor suppressor pathway. Transcriptional profiling indicated that they invoked highly similar responses involving p53 and cell cycle pathways and DNA damage response signaling. Keywords: Stress response Six compounds and one vehicle control,...
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-12666 | biostudies-arrayexpress
GenomicsOncogenic Herpesvirus utilizes stress-induced cell cycle checkpoints for efficient lytic replication.
ChIP-sequencing reads from Oncogenic Herpesvirus utilizes stress-induced cell cycle checkpoints for efficient lytic replication, accepted to PLOS Pathogens
ORGANISM(S): Homo sapiens 
2016-06-01 | E-MTAB-4356 | biostudies-arrayexpress
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