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TranscriptomicsA microRNA microarray analysis of C.elegans Parkinsons disease models
MicroRNAs (miRNAs) play an important role in human brain development and maintenance. To search for miRNAs potentially involved with molecular mechanisms in the pathogenesis of Parkinsons disease (PD), we utilized miRNA microarrays to identify expression changes of 115 annotated Caenorhabditis elega...
ORGANISM(S): Caenorhabditis elegans 
2010-06-20 | E-GEOD-14899 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in ahr-1 mutants compared to wild-type C. elegans
The aryl hydrocarbon receptor (AHR) functions in higher organisims in development, metabolism and toxic responses. Its Caenorhabditis elegans (C. elegans) ortholog, AHR-1, facilitates neuronal development, growth and movement. We investigated the effect of AHR mutation on the transcriptional profile...
ORGANISM(S): Caenorhabditis elegans 
2014-09-19 | E-GEOD-61537 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C. elegans rrf-3 and eri-1 mutants
RRF-3 and ERI-1 are first identified proteins required for accumulation of at least some endogenous secondary siRNAs in C.elegans. Genome wide gene expression analysis was performed on L4 stage rrf-3 and eri-1 mutant C. elegans to study effects caused by loss of these proteins. Mutant rrf-3 and eri-...
ORGANISM(S): Caenorhabditis elegans 
2008-06-16 | E-GEOD-8659 | biostudies-arrayexpress
TranscriptomicsAhR mutant vs N2 wild-type C.elegans, in L1 larval stage
Expression profiles of AhR mutant vs N2 wild-type C.elegans, in L1 larval stage compared by using 23232 feature WUSTL microarray 4 ahr-mutant worm samples compared to 3 wild-type samples. Total RNAs purified and reverse transcribed to cDNA and labeled with Cy3-dUTP, and then hybridized on microarray...
ORGANISM(S): Caenorhabditis elegans 
2010-05-16 | E-GEOD-16036 | biostudies-arrayexpress
TranscriptomicsExpression Data from Ectopic expression of SUMO-1 in C. elegans
Transgenic C. elegans strains that express human SUMO-1 under the control of pan-neuronal (aex-3) or pan muscular (myo-4) promoters were assayed for gene expression changes. Control N2 non transgenic worms were compared to aex-3::His-SUMO-1 and myo-4::His-SUMO-1 worms in 3 biological replicate popul...
ORGANISM(S): Caenorhabditis elegans 
2011-01-31 | E-GEOD-19972 | biostudies-arrayexpress
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