Sort   by:  
 Page size 
TranscriptomicsInositol regulation with Cryptococcus neoformans JEC21 70-mer whole genome array
Cryptococcus neoformans is the most common cause of fungal meningitis, with high mortality and morbidity. The reason for the frequent occurrence of Cryptococcus infection in the central nervous system (CNS) is poorly understood. In this study, we find that inositol plays an important role in the tra...
ORGANISM(S): Cryptococcus neoformans 
2012-09-29 | E-GEOD-41211 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse fibroblast cells transfected with zinc-inducible C/EBP expression vectors identifies Per2 as a gene implicated in myeloid leukemia
The zinc-inducible C/EBP expression vectors pMTa, pMTb, pMTd and pMTe were constructed by cloning the human C/EBPa, C/EBPb, C/EBPd and C/EBPe cDNAs, respectively, into the pMTCB6+ vector. NIH 3T3 cells were transfected with zinc-inducible C/EBP vectors as well as control empty vector using the GeneP...
ORGANISM(S): Mus musculus 
2007-12-04 | E-GEOD-2188 | biostudies-arrayexpress
TranscriptomicsRoles for microRNAs, miR-93 and miR-130b, and TP53INP1 tumor suppressor in cell growth dysregulation by HTLV-1
This is to study the role of miRNAs in human T-cell leukemia virus-1, HTLV-1. In this study, we profiled the miRNA expression in virus transformed human cell lines and primary peripheral blood mononuclear cells (PBMCs) from Adult-T cell leukemia (ATL) patients using the RNA-primed, array-based Kleno...
ORGANISM(S): Homo sapiens 
2008-06-06 | E-GEOD-11577 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse small intestines
Rb and E2F are thought to play antagonistic roles in celll proliferation. However, this model is based mostly from in vitro cell culture systems. We used small intestines to test this model in vivo. We found that deletion of E2f1-3 in the small intestine of mice suppressed the ectopic expression o...
ORGANISM(S): Mus musculus 
2010-01-19 | E-GEOD-16454 | biostudies-arrayexpress
TranscriptomicsIdentification of a Potential Ovarian Cancer Stem Cell Gene Expression Profile from Advanced Stage Papillary Serous Ovarian Cancer
To identify the potential ovarian cancer stem cell gene expression profile from isolated side population of fresh ascites obtained from women with high-grade advanced stage papillary serous ovarian adenocarcinoma Microarrays were used to interrogate the differentially expressed genes between side po...
ORGANISM(S): Homo sapiens 
2011-11-23 | E-GEOD-33874 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae (budding yeast) mutants reveals Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and programmed cell death
Changes in the transcriptome of Isc1p deficient mutants. The inositolphosphosphingolipid phospholipase C (Isc1p) of Saccharomyces cerevisiae belongs to the family of neutral sphingomyelinases that generates the bioactive sphingolipid ceramide. In this work the role of Isc1p in oxidative stress resis...
ORGANISM(S): Saccharomyces cerevisiae 
2008-02-05 | E-MEXP-1136 | biostudies-arrayexpress
TranscriptomicsIdentification of Novel Therapeutic Targets in Microdissected Clear Cell Ovarian Cancers
To identify the gene signature accounting for the distinct clinical outcomes in ovarian clear cell cancer patients Clear cell ovarian cancer is an epithelial ovarian cancer histotype that is less responsive to chemotherapy and carries poorer prognosis than serous and endometrioid histotypes. Despite...
ORGANISM(S): Homo sapiens 
2011-05-24 | E-GEOD-29450 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat severed medial collateral ligament following injury
Gene Expression Profiling of Severed Rat Medial Collateral Ligament at 1, 2, 4, 7,1 0, and 14 days Following Injury with Control and Cultured Ligament Fibroblasts and Rat Universal Reference RNA; The aim of this study was to assess the genes involved in the repair of the the dense connective tissue ...
ORGANISM(S): Rattus norvegicus 
2008-04-05 | E-GEOD-10720 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HUVEC and OVCA429 cell lines treated with recombinant MAGP2
Identification of signaling events contributing to the effect of recombinant MAGP2 on HUVECs and OVCA429. We used microarrays to identify the signaling events and up-regulated genes associated with MAGP2. Experiment Overall Design: To explore the consequences of recMAGP2-induced signaling in ovarian...
ORGANISM(S): Homo sapiens 
2009-10-27 | E-GEOD-18373 | biostudies-arrayexpress
UnknownPhase I Trial of the Human Double Minute 2 Inhibitor MK-8242 in Patients With Advanced Solid Tumors.
Not available
S-EPMC5946729 | biostudies-literature
Sort   by:  
 Page size