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UnknownA Ratiometric and Colorimetric Hemicyanine Fluorescent Probe for Detection of SO2 Derivatives and Its Applications in Bioimaging.
Not available
S-EPMC6865185 | biostudies-literature
ProteomicsTandem affinity purification and Multidimensional Protein Identification Technology to identify USP44 interacting proteins
Nuclear extracts were isolated from 293T cells that stably express USP44 fused with N-terminal FLAG and HA affinity tags (FH-USP44), and then analyzed by tandem affinity purification (TAP) followed by Multidimensional Protein Identification Technology (MudPIT) to uncover USP44 associated proteins. T...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000080144 | MassIVE
GenomicsGenomic targets of the KRAB and scan domain-containing zinc finger protein 263 (ZNF263).
Half of all human transcription factors use C2H2 zinc finger domains to specify site-specific DNA binding and yet very little is known about their role in gene regulation. Based on in vitro studies, a zinc finger code has been developed that predicts a binding motif for a particular zinc finger fact...
ORGANISM(S): Homo sapiens 
2009-12-03 | E-GEOD-19235 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression differences between GT1, RH-ERP2009 and RH-JSR
Previous studies have shown that continuous in vitro passage can result in changes to the global gene expression profiles in mammalian cells. To examine the extent of gene expression differences between highly homologous type I strains, we took advantage of the T. gondii Affymetrix microarray conta...
ORGANISM(S): Toxoplasma gondii 
2010-06-20 | E-GEOD-16115 | biostudies-arrayexpress
TranscriptomicsGene expression response to the antifungal compound sampangine in C. albicans
Sampangine, a plant-derived alkaloid found in the Annonaceae family, exhibits strong inhibitory activity against the opportunistic fungal pathogens Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus. In the present study, transcriptional profiling experiments coupled with the analy...
ORGANISM(S): Candida albicans 
2010-05-26 | E-GEOD-10075 | biostudies-arrayexpress
ProteomicsIP-MS identification of protein interaction for Na (+), K (+)-ATPase beta1 subunit
This project aims to identify proteins that may interact with the sodium potassium pump (ATPase) beta1 subunit in the human lung.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-02-02 | MSV000084881 | MassIVE
ProteomicsPrion MRM assay development and clinical study
Therapies currently in preclinical development for prion disease seek to lower prion protein (PrP) expression in the brain. Trials of such therapies are likely to rely on quantification of PrP in cerebrospinal fluid (CSF) as a pharmacodynamic biomarker and possibly as a trial endpoint. Studies using...
ORGANISM(S): Homo Sapiens Rattus Norvegicus Mus Musculus Macaca Fascicularis 
2019-11-19 | PXD014781 | panorama
TranscriptomicsPyrococcus furiosus crRNAs associated with Cmr, Csa and Cst CRISPR-Cas systems
CRISPR-Cas immune systems function to defend prokaryotes against potentially harmful mobile genetic elements including viruses and plasmids. The multiple CRISPR-Cas systems (Types I, II, III) each recognize and target destruction of foreign invader nucleic acids via structurally and functionally div...
ORGANISM(S): Pyrococcus furiosus 
2015-07-10 | E-GEOD-65781 | biostudies-arrayexpress
TranscriptomicsGenome-wide identification of Streptococcus pneumoniae genes essential for the development of experimental meningitis
We applied genomic array footprinting (GAF) in the search for genes of S. pneumoniae essential during the establishment and progression of experimental meningitis. Four libraries with a total of 6,000 independent TIGR4 marinerT7 transposon mutants were injected intra-cisternally in rabbits, and cere...
ORGANISM(S): Streptococcus pneumoniae 
2010-11-16 | E-GEOD-21729 | biostudies-arrayexpress
ProteomicsDiversity and specificity of extracellular proteome in the cellulolytic bacterium Caldicellulosiruptor bescii is driven by the nature of the cellulosic substrate
Diversity and specificity of extracellular proteome in the cellulolytic bacterium Caldicellulosiruptor bescii is driven by the nature of the cellulosic substrate
ORGANISM(S): Caldicellulosiruptor Bescii (ncbitaxon:31899) 
2017-12-22 | MSV000081856 | MassIVE
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