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TranscriptomicsImpaired Chromatin Remodelling at STAT1-Regulated Promoters Leads to Global Unresponsiveness of Toxoplasma gondii-Infected Macrophages to IFN-Gamma
Intracellular pathogens including the apicomplexan and opportunistic parasite Toxoplasma gondii profoundly modify their host cells in order to establish infection. We have shown previously that intracellular T. gondii inhibit up-regulation of regulatory and effector functions in murine macrophages (...
ORGANISM(S): Mus musculus 
2012-01-25 | E-GEOD-28499 | biostudies-arrayexpress
TranscriptomicsState- and trait-specific gene expression in euthymia and mania
Gene expression profiles of bipolar disorder (BD) patients were assessed during both a manic and a euthymic phase and compared both intra-individually, and with the gene expression profiles of controls. 11 BD patients were assessed in their manic as well as in their euthymic phase. Comparison of gen...
ORGANISM(S): Homo sapiens 
2014-09-04 | E-GEOD-46416 | biostudies-arrayexpress
ProteomicsPhosphoproteomics of the developing heart identifies PERM1 - an outer mitochondrial membrane protein
Heart development relies on PTMs that control cardiomyocyte proliferation, differentiation and cardiac morphogenesis. We generated a map of phosphorylation sites during the early stages of cardiac postnatal development in mice; we quantified over 10,000 phosphorylation sites and 5000 proteins that w...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-07-21 | MSV000085796 | MassIVE
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