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TranscriptomicsEffects of dexamethasone on human skeletal muscle and adipose tissue
Context: Glucocorticoids are frequently prescribed drugs with important side-effects such as glucose intolerance and tissue remodelling. Objective: The goal was to explore the molecular basis of the crosstalk between adipose tissue and skeletal muscle during short term glucocorticoid treatment. Des...
ORGANISM(S): Homo sapiens 
2011-11-28 | E-GEOD-17992 | biostudies-arrayexpress
TranscriptomicsGW7647 and Rosiglitazone treated human differentiated adipocytes
Objective : This work aimed at characterizing PPARα involvement in metabolism regulation and at comparing PPARα and PPARγ roles in human white adipocytes. Research Design and Methods : Profiling of gene expression alterations was assessed with microarrays and RT-qPCR. Primary cultures of human adipo...
ORGANISM(S): Homo sapiens 
2010-04-11 | E-GEOD-15862 | biostudies-arrayexpress
TranscriptomicsEffects of a 8-week training on human skeletal muscle
Context: Exercise training is a plausible model for identification of molecular mechanisms that cause metabolic-related changes in human skeletal muscle. Objective: The goal was to explore the molecular basis of the adaptation of skeletal muscle to exercise training. Design and Intervention: Obes...
ORGANISM(S): Homo sapiens 
2012-12-10 | E-GEOD-40551 | biostudies-arrayexpress
TranscriptomicsSubcutaneous adipose tissue (SAT) gene expression patterns between weight control and regaining weight subjects
Objective: This work aimed at identifying and characterizing differences in subcutaneous adipose tissue (SAT) gene expression patterns between subjects succeeding weight control against subjects regaining weight 6 months after a low calorie diet program. Methods: Weight-reduced obese subjects from 8...
ORGANISM(S): Homo sapiens 
2010-09-30 | E-GEOD-19494 | biostudies-arrayexpress
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