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MetabolomicsEvidence of altered fatty acid metabolism in dogs with naturally occurring valvular heart disease and congestive heart failure

INTRODUCTION: Myxomatous mitral valve disease (MMVD) is the most common cardiac condition in adult dogs. The disease progresses over several years and affected dogs may develop congestive heart failure (HF). Research has shown that myocardial metabolism is altered in cardiac dise...

2022-03-31 | MTBLS716 | MetaboLights
MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
ProteomicsQuantitative proteomics of the infectious and replicative forms of Chlamydia trachomatis L2
The obligate intracellular developmental cycle of Chlamydia trachomatis presents significant challenges in defining its proteome. In this study we have applied quantitative proteomics to both the intracellular reticulate body (RB) and the extracellular elementary body (EB) from C. trachomatis. We...
ORGANISM(S): Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B) 
2016-06-28 | PXD003025 | Pride
Reticulate body Elementary body L2 Chlamydia trachomatis 
UnknownA barley pan-transcriptome reveals layers of genotype-dependent transcriptional complexity.
Not available
S-EPMC11821519 | biostudies-literature
UnknownGenomic signatures of barley breeding for environmental adaptation to the new continents.
Not available
S-EPMC10440980 | biostudies-literature
UnknownThe barley pan-genome reveals the hidden legacy of mutation breeding.
Not available
S-EPMC7759462 | biostudies-literature
UnknownConstruction of a map-based reference genome sequence for barley, Hordeum vulgare L.
Not available
S-EPMC5407242 | biostudies-literature
MetabolomicsProtein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights
UnknownStructural variation in the pangenome of wild and domesticated barley.
Not available
S-EPMC11655362 | biostudies-literature
UnknownDiagnostic uncertainty presented barriers to the timely management of acute thrombotic thrombocytopenic purpura in the United Kingdom between 2014 and 2019.
Not available
S-EPMC9314944 | biostudies-literature
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