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We used RNA-Seq to identify differential gene expression in LAP+ vs. LAP- Gamma-delta T-cells. We report a signature of 407 genes that were enriched in TCRgd+LAP+ vs. TCRgd+LAP- cells with p<0.05. Among the up-regulated genes, we found increased expression of genes related to antigen presentation, i...
ORGANISM(S): Mus musculus 
Lactiplantibacillus plantarum strain:Lap Genome sequencing
BACKGROUND & AIMS: C/EBPbeta is involved in numerous process as carcinogenesis but its role is still not clear due to the existence of an active form (LAP) and an inhibitory form (LIP) of this transcription factor. The main goals of the present research were (i) the identification of genes inversely...
ORGANISM(S): Homo sapiens 
To gain insight into the gene signatures directly mediated by LAP (CEBPB) for cancer cell progression, we performed RNA-seq in LAP-HepG2 versus control cells.
ORGANISM(S): Homo sapiens 
We used RNA-Seq to identify differential gene expression in LAP+ vs. LAP- Gamma-delta T-cells. We report a signature of 407 genes that were enriched in TCRgd+LAP+ vs. TCRgd+LAP- cells with p<0.05. Among the up-regulated genes, we found increased expression of genes related to antigen presentation, i...
ORGANISM(S): Mus musculus 
2015-09-17 | GSE73077 | GEO
RNA seq of HepG2 cells Ctrl vs LAP (CEBPB) OE
Expression analysis of TCRgd+LAP+ versus TCRgd+LAP- cells
BACKGROUND & AIMS: C/EBPbeta is involved in numerous process as carcinogenesis but its role is still not clear due to the existence of an active form (LAP) and an inhibitory form (LIP) of this transcription factor. The main goals of the present research were (i) the identification of genes inversely...
ORGANISM(S): Homo sapiens 
2009-02-27 | GSE15010 | GEO
C/EBPβ plays a major role in numerous biological processes but unfortunately its precise role is not still clear and conflicting studies showed that this transcription factor could have contradictory functions. These latter arise from the complexity of mechanisms regulating C/EBPβ activity. Indeed, ...
ORGANISM(S): Homo sapiens 
PECs from wild-type, NF-IL6KO and KI(LAP) mice were stimulated with or without LPS+IFN-gamma for 12h. We used microarrays to check the difference of gene induction among wild type, KO and KI mice. Experiment Overall Design: Peritoneal macrophages were collected for RNA extraction and hybridization o...
ORGANISM(S): Mus musculus 
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