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TranscriptomicsmiRNA profiling of human acute myeloid leukaemia Kasumi-1 cell line CD34+38- compartment.
The t(8;21) Acute Myeloid Leukaemia (AML) Kasumi-1cell line with N822K KIT mutation, is a model system for leukemogenesis. As AML initiating cells reside in the CD34+CD38- fraction, we addressed the refined cytogenomic characterization and miRNA expression of Kasumi-1 cell line and its FACS-sorted...
ORGANISM(S): Homo sapiens 
2010-02-19 | E-TABM-909 | biostudies-arrayexpress
TranscriptomicsAnalysis of copy number changes and complex rearrangements in patients with congenital abnormalities
Chromothripsis represents a novel phenomenon in the structural variation landscape of cancer genomes. Here, we analyzed the genomes of ten patients with congenital disease that were preselected to carry complex chromosomal rearrangements (CCRs) with more than two breakpoints. The rearrangements disp...
ORGANISM(S): Homo sapiens 
2012-05-10 | E-GEOD-37906 | biostudies-arrayexpress
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