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TranscriptomicsX chromosome dosage compensation via enhanced transcriptional elongation in Drosophila males (Control & MSL2 RNAi)
MSL (Male-specific lethal) complex increases transcription on the single X chromosome of Drosophila males in order to equalize expression of X-linked genes between males (XY) and females (XX). The increase in transcript levels correlates with MSL- dependent acetylation of histone H4 at K16 within th...
ORGANISM(S): Drosophila melanogaster 
2011-03-03 | E-GEOD-25887 | biostudies-arrayexpress
TranscriptomicsX chromosome dosage compensation via enhanced transcriptional elongation in Drosophila males (Untreated)
MSL (Male-specific lethal) complex increases transcription on the single X chromosome of Drosophila males in order to equalize expression of X-linked genes between males (XY) and females (XX). The increase in transcript levels correlates with MSL- dependent acetylation of histone H4 at K16 within th...
ORGANISM(S): Drosophila melanogaster 
2010-12-22 | E-GEOD-25321 | biostudies-arrayexpress
TranscriptomicsDrosophila MSL complex globally acetylates H4 Lys16 on the male X chromosome for dosage compensation
Drosophila MSL complex binds the single male X chromosome to upregulate gene expression to equal that from the two female X chromosomes. However, it has been puzzling that ~25% of transcribed genes on the X do not stably recruit MSL complex. Here, we find that almost all active genes on the X are ...
ORGANISM(S): Drosophila melanogaster 
2009-06-10 | E-GEOD-14884 | biostudies-arrayexpress
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