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TranscriptomicsPKC isoforms - MDA-MB-231
PKCalpha, delta and epsilon were downregulated in MDA-MB-231 cells and mRNA expression was analyzed
ORGANISM(S): Homo sapiens 
2011-03-01 | E-MTAB-462 | biostudies-arrayexpress
TranscriptomicsEffects of siRNA targeting PRKCD in breast cancer cells
The aim was to identify genes that were commonly influenced by a siRNA targeting PRKCD in breast cancer cell lines. MDA-MB-468 and BT-549 breast cancer cell lines were treated with control siRNA or siRNA targeting PRKCD. Three samples in each group were analyzed.
ORGANISM(S): Homo sapiens 
2015-03-01 | E-GEOD-55503 | biostudies-arrayexpress
TranscriptomicsCathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis
Cavitation in tuberculosis (TB) enables highly efficient person-to-person aerosol transmission. Currently, a number of hypotheses exist regarding the mechanisms underlying this process. To explore this process, we undertook an unbiased next-generation transcriptional analysis of samples from cavity ...
ORGANISM(S): Oryctolagus cuniculus 
2015-11-03 | E-GEOD-68206 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of M.tuberculosis using RNA-seq indicates WhiB6 repression of dormancy associated genes
Tuberculosis is an infectious disease, with latent infection with Mycobacterium tuberculosis (M.tb) affecting 1/3 of humanity. It can remain quiescent for long time, making eradication very difficult. To do so, M.tb need to carefully orchestrate its gene expression to survive immune response and sta...
ORGANISM(S): Mycobacterium tuberculosis CDC1551 
2013-09-18 | E-GEOD-40941 | biostudies-arrayexpress
TranscriptomicsAnalysis of compartment-specific gene expression in breast cancer tumors
Triple-negative primary breast cancer tumors, rich in inflammatory stroma, were laser microdissected and global mRNA expression was analyzed in stroma compartment, cancer cell compartment, and in total tumor tissue. Three FFPE breast cancer tumors wer laser microdissected and the cancer cell and str...
ORGANISM(S): Homo sapiens 
2015-05-01 | E-GEOD-59772 | biostudies-arrayexpress
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