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UnknownAccumulation of ether phospholipids in induced pluripotent stem cells and oligodendrocyte-lineage cells established from patients with Sjogren-Larsson syndrome.
Not available
S-EPMC11608845 | biostudies-literature
TranscriptomicsChromatin IP of POF, HP1 and H3K9ac in S2 cells and salivary glands.
Two chromosome-targeting and gene regulatory systems are present in Drosophila melanogaster. The male X-chromosome is targeted by the male-specific lethal complex believed to mediate the two-fold up-regulation of the X-linked genes. The highly heterochromatic 4th chromosome is specifically targeted ...
ORGANISM(S): Drosophila melanogaster 
2007-10-02 | E-GEOD-8296 | biostudies-arrayexpress
MetabolomicsEvaluation of sample preparation methods for NMR-based metabolomics of cow milk
The quality of milk metabolome analyzed by nuclear magnetic resonance (NMR) is greatly influenced by the way samples are prepared. Although this analytical method is increasingly used to study milk metabolites, a thorough examination of available sample preparation protocols for milk has not been re...
2019-06-13 | MTBLS623 | MetaboLights
TranscriptomicsTranscript profiling in S2 cells and salivary glands.
Two chromosome-targeting and gene regulatory systems are present in Drosophila melanogaster. The male X-chromosome is targeted by the male-specific lethal complex believed to mediate the two-fold up-regulation of the X-linked genes. The highly heterochromatic 4th chromosome is specifically targeted ...
ORGANISM(S): Drosophila melanogaster 
2007-10-02 | E-GEOD-8297 | biostudies-arrayexpress
TranscriptomicsBuffering and proteolysis are induced upon segmental haploidy in Drosophila melanogaster.
Aneuploidy, i.e., variation in the number of individual chromosomes (chromosomal aneuploidy) or chromosome segment (segmental aneuploidy) is associated with developmental abnormalities and reduced fitness in all species examined, is the leading cause of miscarriages and mental retardations and a hal...
ORGANISM(S): Drosophila melanogaster 
2012-04-04 | E-GEOD-34400 | biostudies-arrayexpress
TranscriptomicsHP1a recruitment to promoters is independent of H3K9 methylation in Drosophila melanogaster
Heterochromatin protein 1 (HP1) proteins are important regulators of heterochromatin mediated gene silencing and chromosome structure and it is well known as the reader of the heterochromatin mark methylation of histone H3 lysine 9 (H3K9me). In Drosophila three different histone lysine methyl transf...
ORGANISM(S): Drosophila melanogaster 
2012-12-21 | E-GEOD-38366 | biostudies-arrayexpress
TranscriptomicsHP1a, Su(var)3-9, SETDB1 and POF stimulate or repress gene expression depending on genomic position, gene length and expression pattern in Drosophila melanogaster
Heterochromatin protein 1a (HP1a) is a chromatin associated protein that has been well studied in many model organisms, such as Drosophila, where it is a determining factor for classical heterochromatin. HP1a is associated with the two histone methyltransferases SETDB1 and Su(var)3-9, which mediate ...
ORGANISM(S): Drosophila melanogaster 
2013-04-05 | E-GEOD-43478 | biostudies-arrayexpress
UnknownIdentification of Homozygous Likely Pathogenic Variant of ALDH3A2 in a Korean Boy with Sjogren-Larsson Syndrome.
Not available
S-EPMC5700155 | biostudies-literature
GenomicsDrosophila melanogaster
Buffering of segmental and chromosomal aneuploidies in Drosophila melanogaster
PRJNA111665 | ENA
TranscriptomicsTranscriptome profiling of wild type and Pof mutant Drosophila melanogaster females
In Drosophila, two chromosome-wide compensatory systems have been characterized; the dosage compensation system acting on the male X-chromosome and the chromosome specific regulation of genes located on the heterochromatic 4th chromosome. Dosage compensation in Drosophila is accomplished by hypertra...
ORGANISM(S): Drosophila melanogaster 
2012-05-30 | E-GEOD-28513 | biostudies-arrayexpress
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