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MetabolomicsHuman basal cell carcinoma samples analysed by laser desorption rapid evaporative ionisation mass spectrometry (LD-REIMS) imaging

Laser ablation rapid evaporative ionisation mass spectrometry (LA-REIMS) was used to analyse human basal cell carcinoma (BCC) samples. 14 samples are presented here, along with H&E-stained histological images.

2025-07-28 | MTBLS12786 | MetaboLights
ProteomicsWavelength Dependence of Intact Protein Extraction Using Femtosecond Laser Ablation
Raw files for the paper named: Wavelength Dependence of Intact Protein Extraction Using Femtosecond Laser Ablation
ORGANISM(S): Mastigocladopsis Repens Rhodopsin Equine Myoglobin Lysozyme From Chicken Egg White 
2025-03-04 | MSV000097234 | MassIVE
ProteomicsDirect 3D sampling of the embryonic mouse head: Layer-wise nanosecond infrared laser (NIRL) ablation from scalp to cortex for spatially resolved proteomics
Common workflows in bottom-up proteomics require homogenization of tissue samples giving to get access to the biomole-cules within the cells. The homogenized tissue samples often contain many different cell types, thereby representing an average of the natural proteome composition and rare cell type...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD043011 | Pride
Nirl ablation Spatial proteomics Tissue sampling Bottom-up proteomics 
TranscriptomicsThe effects of LH ablation/replacement versus steroid ablation/replacement on gene expression in primate corpora lutea
This study was designed to provide a genome-wide analysis of the effects of luteinizing hormone (LH) ablation/replacement versus steroid ablation/replacement on gene expression in the developed corpus luteum (CL) in primates during the menstrual cycle. Naturally cycling, female rhesus monkeys were l...
ORGANISM(S): Macaca mulatta 
2009-01-25 | E-GEOD-12281 | biostudies-arrayexpress
ProteomicsSampling and homogenization of nanoliter tissue with a nanosecond infrared laser (NIRL) for mass spectrometric proteomics
It was recently shown that ultrashort pulse infrared (IR) lasers, operating at the wavelength of the OH vibration stretching band of water, are highly efficient at softly sampling and homogenizing biological tissue. We utilized a nanosecond infrared laser (NIRL) for tissue sampling and homogenizatio...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-17 | PXD027700 | Pride
Laser ablation Tissue sampling  nanosecond infrared laser Proteomics  mass spectrometry 
UnknownMechanisms of ultrafast GHz burst fs laser ablation.
Not available
S-EPMC10032593 | biostudies-literature
UnknownTransmissive Mode Laser Micro-Ablation Performance of Ammonium Dinitramide-Based Liquid Propellant for Laser Micro-Thruster.
Not available
S-EPMC10303727 | biostudies-literature
ProteomicsImpact of intermittent lead exposure on hominid brain evolution
Lead Exposure and Human Brain Evolution: A 2-Million-Year Perspective This study reveals that lead exposure was pervasive throughout human evolution, not just a modern phenomenon. Researchers analyzed 51 fossil teeth from multiple hominid species spanning 2+ million years across three continents, fi...
ORGANISM(S): Homo sapiens (Human) 
2025-10-27 | PXD067623 | Pride
Lead exposure  hominid brain evolution  nova1–foxp2 axis 
ProteomicsTissue sampling and homogenization with NIRL enables spatially resolved cell layer specific proteomic analysis of the murine intestine
For investigating the molecular physiology and pathophysiology in organs the most exact data will be obtained, if not organ specific cell lines are analysed or the whole organ is homogenized, followed by the analysis of its biomolecules, but if the morphological organisation of the organ can be addr...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-22 | PXD033584 | Pride
Colon 3d Mouse Laser-ablstion Lc-ms/ms 
UnknownTreatment of vulvar and vaginal dysplasia: plasma energy ablation versus carbon dioxide laser ablation.
Not available
S-EPMC9415775 | biostudies-literature
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