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TranscriptomicsTranscriptome Analysis of Human Peripheral Blood Mononuclear Cells Exposed to Lassa Virus and to the Reassortant ML29, a Vaccine Candidate
The virulent Lassa fever virus (LASV) and the non-pathogenic Mopeia virus (MOPV) infect rodents and incidentally people in West Africa. The mechanism of LASV damage in human beings is unclear. A live-attenuated reassortant of MOPV and LASV protects rodents and primates from Lassa fever disease. Peri...
ORGANISM(S): Homo sapiens 
2013-11-05 | E-GEOD-41300 | biostudies-arrayexpress
TranscriptomicsTranscriptional Profiling in Non-Human Primates Infected With Lassa Virus to Understand the Immune Response to Lassa Infection
Lassa fever virus (LASV) is a significant human pathogen that is endemic to several countries in West Africa. Infection with Lassa leads to the development of hemorrhagic fever in a significant number of public health cases and it is considered a potential bioweapon. Little is known about the compl...
ORGANISM(S): Macaca fascicularis 
2013-06-18 | E-GEOD-41752 | biostudies-arrayexpress
GenomicsLassa virus Josiah
Deep mutational scanning of the Lassa virus Josiah strain glycoprotein complex (GPC)
PRJNA1071644 | ENA
ProteomicsRNA to rule them all: Critical steps in Lassa virus ribonucleoparticle assembly and recruitment
Lassa virus is a negative-strand RNA virus with only four structural proteins that causes periodic outbreaks in West Africa. The nucleoprotein (NP) encapsidates the viral genome, forming the ribonucleoparticles together with the viral RNA and the L protein, which have to be continuously restructured...
ORGANISM(S): Lassa mammarenavirus 
2023-12-18 | PXD040186 | Pride
Native ms Lassa virus 
GenomicsMammarenavirus lassaense isolate:Lassa virus
Genomic characterization of clinical Lassa virus isolates from 2017-2023 transmission seasons in Sierra Leone
PRJNA966213 | ENA
GenomicsMammarenavirus lassaense strain:Mopeia-Lassa 29
Assessing the variation of an attenuated Lassa vaccine after passage in vivo
PRJNA73681 | ENA
TranscriptomicsGene expression associated with liver metabolism during viral hemorrhagic fever
Rhesus macaques (Macaca mulatta) infected with a lethal dose of lymphocytic choriomeningitis virus-strain WE (LCMV-WE) provide a model for Lassa fever virus infection of man. Like Lassa fever in human beings, disease begins with flu-like symptoms but can progress to morbidity fairly rapidly. Previ...
ORGANISM(S): Macaca mulatta 
2010-06-16 | E-GEOD-12254 | biostudies-arrayexpress
GenomicsTranscriptional Profiling in Non-Human Primates Infected With Lassa Virus to Understand the Immune Response to Lassa Infection
Transcriptional Profiling in Non-Human Primates Infected With Lassa Virus to Understand the Immune Response to Lassa Infection
PRJNA178111 | ENA
UnknownAnalysis of synonymous codon usage bias of Lassa virus.
Not available
S-EPMC11815952 | biostudies-literature
GenomicsMammarenavirus lassaense
Lassa Virus Sequencing
PRJNA482054 | ENA
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