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TranscriptomicsGlobal Profiling in Vestibular Schwannomas Shows Critical Deregulation of MicroRNAs and Upregulation in those included in Chromosomal Region 14q32
Background: Vestibular Schwannomas are benign tumors that arise from Schwann cells in the VIII cranial pair and usually present NF2 gene mutations and/or loss of heterozygosity on chromosome 22q. Deregulation has also been found in several genes, such as ERBB2 and NRG1. MicroRNAs are non-coding RNAs...
ORGANISM(S): Homo sapiens 
2014-03-24 | E-GEOD-43571 | biostudies-arrayexpress
TranscriptomicsMicroarray Analysis in Vestibular Schwannomas
Vestibular Schwannomas are benign neoplasms that arise from the vestibular nerve. The hallmark of these tumors is the biallelic inactivation of NF2. Transcriptomic alterations, such as the Nrg1/ErbB2 pathway, have been described in Schwannomas. Here, we have performed a whole transcriptomic analysis...
ORGANISM(S): Homo sapiens 
2013-03-01 | E-GEOD-39645 | biostudies-arrayexpress
TranscriptomicsGlobal expression profile in a combined study in low grade meningiomas and schwannomas shows upregulation in PDGF, CDH1, SLIT2 and MET.
Background: Schwannomas and grade I meningiomas are non-metastatic neoplasms that shares the common mutation of gene NF2. They usually appear in Neurofibromatosis type 2 patients. Currently, there is no drug treatment available for both tumors, so the use of wide expression technologies is crucial t...
ORGANISM(S): Homo sapiens 
2015-08-30 | E-GEOD-54934 | biostudies-arrayexpress
UnknownCIBERER: Spanish national network for research on rare diseases: A highly productive collaborative initiative.
Not available
S-EPMC9305285 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
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