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ProteomicsSchlafen family member 5 (SLFN5) regulates LAT1-mediated mTOR activation in castration-resistant prostate cancer (PART 2)
Androgen-deprivation therapy (ADT) is the standard of care for the treatment of non-resectable prostate cancer (PCa). Despite high treatment efficiency, most patients ultimately develop lethal castration-resistant prostate cancer (CRPC). In this study, we perform a comparative proteomic analysis of ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD021405 | Pride
Castration-resistant prostate cancer Lat1/mtor signalling Cancer metabolism Proteomics 
ProteomicsSchlafen family member 5 (SLFN5) regulates LAT1-mediated mTOR activation in castration-resistant prostate cancer (PART 1)
Androgen-deprivation therapy (ADT) is the standard of care for the treatment of non-resectable prostate cancer (PCa). Despite high treatment efficiency, most patients ultimately develop lethal castration-resistant prostate cancer (CRPC). In this study, we perform a comparative proteomic analysis of ...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2022-04-06 | PXD021428 | Pride
Castration-resistant prostate cancer Lat1/mtor signalling Cancer metabolism Cancer proteomics 
UnknownThe catalytic subunit of the system L1 amino acid transporter (slc7a5) facilitates nutrient signalling in mouse skeletal muscle.
Not available
S-EPMC3935884 | biostudies-literature
UnknownAcetylation turns leucine into a drug by membrane transporter switching.
Not available
S-EPMC8338929 | biostudies-literature
TranscriptomicsRNA sequencing of WT and Uhrf1 KO iNKT cells
Deletion of Uhrf1 resulted in stage 1-specific defects during iNKT cell development. To investigate the molecular mechanism, we sorted WT and Uhrf1-KO stage 1 iNKT cells and performed RNA-seq. By comparing gene expression profile, we found metabolic defects in Uhrf1-KO stage 1 iNKT cells. The expres...
ORGANISM(S): Mus musculus 
2016-03-10 | E-GEOD-77941 | biostudies-arrayexpress
ProteomicsCunjie_SLC3A2_TripleTOF6600_Fig4_5
This dataset consists of 40 raw MS files, acquired on a TripleTOF 6600 (AB SCIEX, Concord, Ontario, Canada) mass spectrometer operated in data dependent acquisition (DDA) and SWATH mode. Code for variants with additional NXS/T sites: 255I WTseq: (N365, N381, N424, N506) 256G N273A (+1 site...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000092989 | MassIVE
ProteomicsCunjie_SLC3A2_Agilent6550_FigS3
This dataset consists of 8 raw MS files, acquired on Agilent 6550 iFunnel Q-TOF MS (Agilent Inc., Santa Clara, CA) mass spectrometer operated in Data dependent acquisition (DDA) and target MS/MS mode. Code for variants with additional NXS/T sites: 255I WTseq: (N365, N381, N424, N506) 256G N273...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000092988 | MassIVE
ProteomicsCunjie_SLC3A2_Agilent6550_Fig8_S8
This dataset consists of 29 raw MS files, acquired on Agilent 6550 iFunnel Q-TOF MS (Agilent Inc., Santa Clara, CA) mass spectrometer operated in DDA and target MS/MS mode. Code for variants with additional NXS/T sites: 255I WTseq: (N365, N381, N424, N506) 256G N273A (+1 site) 257A N273A; ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000092985 | MassIVE
ProteomicsCunjie_SLC3A2_Agilent6550_Fig2_S5
This dataset consists of 57 raw MS files acquired on Agilent 6550 iFunnel Q-TOF MS (Agilent Inc., Santa Clara, CA) mass spectrometer operated in data dependent acquisition (DDA) and target MS/MS mode. Code for variants with additional NXS/T sites: 255I WTseq: (N365, N381, N424, N506) 256G N27...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000092980 | MassIVE
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