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TranscriptomicsTranscription profiling of human hMADS cells during adipocyte and osteoblast differentiation
human adipocyte and osteoblast differentiation of hMADS cells
ORGANISM(S): Homo sapiens 
2008-08-08 | E-MARS-10 | biostudies-arrayexpress
TranscriptomicsExpression profiling of primary calvaria osteoblasts treated with miR-195 mimic, rhBMP2 and at different stages of differentiation
Primary calvaria osteoblasts from newborn mice were cultured. Cells were transfected with control and miR-195 mimic. Following serum starvation cells were treated with recombinant human BMP2 and expression was analyzed 4 hours after treatment. Additionally, osteoblast differentiation was induced wit...
ORGANISM(S): Mus musculus 
2014-12-02 | E-MTAB-2450 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse C3H10T1/2 cells treated with Glis3 identifies its role in osteoblast differentiation and adipocyte differentiation
The expression of Glis3 in C3H10T1/2 cells promotes osteoblastic differentiation as indicated by the the induction of increase in alkaline phosphatase activity, an early marker of osteoblast differentiation, and increased expression of osteopontin, a late marker of osteogenesis. Glis3 acts synergist...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5379 | biostudies-arrayexpress
TranscriptomicsWnt inhibitory factor 1 (WIF1) is a marker of osteoblastic differentiation stage and is not silenced by DNA methylation in osteosarcoma
Purpose: We have used microarrays to identify gene expression profiles that distinguish mouse OS cells from normal pre-osteoblast cells and mature osteoblast cells. Methods: Transcriptional profiles of three cell lines derived from tumors from Osx-Cre p53fl/fl Rbfl/fl (fibroblastic OS) mouse model, ...
ORGANISM(S): Mus musculus 
2015-01-29 | E-GEOD-63939 | biostudies-arrayexpress
TranscriptomicsPPAR Controls Gene Expression in MSC Cells
Rosiglitazone (Rosi), a member of the thiazolidinedione class of drugs used to treat type 2 diabetes, activates the adipocyte-specific transcription factor peroxisome proliferator-activated receptor gamma (PPARg). This activation causes bone loss in animals and humans, at least in part due to suppre...
ORGANISM(S): Mus musculus 
2009-01-15 | E-GEOD-10192 | biostudies-arrayexpress
TranscriptomicsGlis3: The role in osteoblast differentiation and adipocyte differentiation
The expression of Glis3 in C3H10T1/2 cells promotes osteoblastic differentiation as indicated by the the induction of increase in alkaline phosphatase activity, an early marker of osteoblast differentiation, and increased expression of osteopontin, a late marker of osteogenesis. Glis3 acts synergist...
ORGANISM(S): Mus musculus 
2007-05-22 | GSE5379 | GEO
UnknownMelatonin promotes osteoblast differentiation by regulating Osterix protein stability and expression.
Not available
S-EPMC5515917 | biostudies-literature
UnknownJagged1 is essential for osteoblast development during maxillary ossification.
Not available
S-EPMC4306467 | biostudies-literature
UnknownExpression and function of Dlx genes in the osteoblast lineage.
Not available
S-EPMC2679944 | biostudies-literature
UnknownA novel library screen identifies immunosuppressors that promote osteoblast differentiation.
Not available
S-EPMC3352976 | biostudies-literature
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