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TranscriptomicsGenetic Analysis of Pathways Regulated by the von Hippel-Lindau Tumor Suppressor in Caenorhabditis elegans
The von Hippel-Lindau (VHL) tumor suppressor functions as a ubiquitin ligase that mediates proteolytic inactivation of hydroxylated a subunits of hypoxia-inducible factor (HIF). Although studies of VHL defective renal carcinoma cells suggest the existence of other VHL tumor suppressor pathways, dysr...
ORGANISM(S): Caenorhabditis elegans 
2005-07-20 | E-GEOD-2963 | biostudies-arrayexpress
UnknownHigh-Resolution Genetic Maps Identify Multiple Type 2 Diabetes Loci at Regulatory Hotspots in African Americans and Europeans.
Not available
S-EPMC5420350 | biostudies-literature
UnknownABCC5 transporter is a novel type 2 diabetes susceptibility gene in European and African American populations.
Not available
S-EPMC4173130 | biostudies-literature
ProteomicsViral lncRNA upregulates multiple A+U-richViral lncRNA upregulates multiple A+U-rich transcripts to promote cell motility and viral dissemination transcripts to promote cell motility and viral dissemination
Long non-coding RNAs are frequently associated with broad modulation of gene expression and thus provide the cell with the ability to synchronize entire metabolic processes. We used transcriptomic and proteomic approaches to investigate whether the most abundant human cytomegalovirus-encoded lncRNA,...
ORGANISM(S): Human herpesvirus 5 strain Merlin Homo sapiens (Human) 
2021-07-27 | PXD022277 | Pride
Cell motility Gene regulation Lncrna A+u rich Transcriptomics Human cytomegalovirus Viral dissemination 
UnknownNew Insights Into Mitochondrial Dysfunction at Disease Susceptibility Loci in the Development of Type 2 Diabetes.
Not available
S-EPMC8385132 | biostudies-literature
UnknownImpact of Adolescent and Young Adult Cancer Expertise in Oncologists on AYA Outcomes in Hodgkin Lymphoma: A Population-Based Study in Ontario, Canada.
Not available
S-EPMC12856524 | biostudies-literature
UnknownThe hazards of genotype imputation when mapping disease susceptibility variants.
Not available
S-EPMC10763476 | biostudies-literature
GenomicsMassive genomic rearrangement acquired in a single catastrophic event during cancer development - samples
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
EGAD00001000002 | EGA
UnknownIdentification and replication of three novel myopia common susceptibility gene loci on chromosome 3q26 using linkage and linkage disequilibrium mapping.
Not available
S-EPMC2556391 | biostudies-literature
GenomicsMassive Genomic Rearrangment Acquired in a Single Catastrophic Event During Cancer Development
Cancer is driven by mutation. Using Agilent exome hybridisation capture and Illumina GA massively parallel sequencing technology, we aim to sequence ~1600 microRNAs plus the protein coding genome of 25 matched human renal cancer samples. Bespoke algorithms are being developed to identify the somatic...
EGAS00000000029 | EGA
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