Orton2009 - Modelling cancerous mutations in
the EGFR/ERK pathway - EGF Model
This model studies the aberrations in
ERK signalling for different cancer mutations. The authors alter a
previously existing EGF model (Brown et al 2004) to include new
interactions that better fit empirical data.
Predicti...
Proctor2005 - Actions of chaperones and their
role in ageing
This model is described in the article:
Modelling the actions of
chaperones and their role in ageing.
Proctor CJ, Soti C, Boys RJ,
Gillespie CS, Shanley DP, Wilkinson DJ, Kirkwood TB.
Mech. Ageing Dev. 2005 Jan; 126(...
ATRX is an X-linked gene of the SWI/SNF family whose role in vivo is currently unknown. Mutations in ATRX cause syndromal mental retardation. ATRX binds to tandem repeat (TR) sequences both in heterochromatin (e.g. telomeres) and euchromatin. Genes associated with these TRs can be dysregulated when ...
Das2010 - Effect of a gamma-secretase
inhibitor on Amyloid-beta dynamics
This model is described in the article:
Modeling effect of a
?-secretase inhibitor on amyloid-? dynamics reveals significant
role of an amyloid clearance mechanism.
Das R, Nachbar RB, Edelstein-Keshet
L...
Kerkhoven2013 - Glycolysis in T.brucei - MODEL A
There are six models (Model A, B, C, C-fruc, D, D-fruc) described in the paper. Model A ( BIOMD0000000513
) is the model developed originally by Achar et al. (2012) ( BIOMD0000000428
), which des...
Kerkhoven2013 - Glycolysis and Pentose Phosphate Pathway in T.brucei - MODEL B
There are six models (Model A, B, C, C-fruc, D, D-fruc) described in the paper. Model A ( BIOMD0000000513
) is the model developed originally by Achar et al. (2012) ( BIOMD00000...
Kerkhoven2013 - Glycolysis and Pentose Phosphate Pathway in T.brucei - MODEL C in fructose medium (with glucosomal ribokinase)
There are six models (Model A, B, C, C-fruc, D, D-fruc) described in the paper. Model A ( BIOMD0000000513
) is the model developed origi...
Kerkhoven2013 - Glycolysis and Pentose Phosphate Pathway in T.brucei - MODEL D in fructose medium (with ATP:ADP antiporter)
There are six models (Model A, B, C, C-fruc, D, D-fruc) described in the paper. Model A ( BIOMD0000000513
) is the model developed original...
Kerkhoven2013 - Glycolysis and Pentose Phosphate Pathway in T.brucei -MODEL C (with glucosomal ribokinase)
There are six models (Model A, B, C, C-fruc, D, D-fruc) described in the paper. Model A ( BIOMD0000000513
) is the model developed originally by Achar et al...
Kerkhoven2013 - Glycolysis and Pentose Phosphate Pathway in T.brucei - MODEL D (with ATP:ADP antiporter)
There are six models (Model A, B, C, C-fruc, D, D-fruc) described in the paper. Model A ( BIOMD0000000513
) is the model developed originally by Achar et al. ...
