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GenomicsLacticaseibacillus paracasei strain:LcA
Lacticaseibacillus paracasei strain:LcA Genome sequencing and assembly
PRJNA195542 | ENA
TranscriptomicsGlobal gene expression analysis of human iPSC-derived Neural Stem Cells (NSC) from LCA patients and unaffected persons
Our purpose was to investigate genes and molecular mechanisms involved in patients with Leber congenital amaurosis (LCA). Fibroblasts from two unrelated clinically-identified patients (Coriell) were reprogrammed to pluripotency by retroviral transduction. These human induced Pluripotent Stem Cells (...
ORGANISM(S): Homo sapiens 
2015-01-21 | E-GEOD-43924 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of human iPSC-derived Retinal Pigmented Epithelial (RPE) cells from LCA patients and unaffected persons
Our purpose was to investigate genes and molecular mechanisms involved in patients with Leber congenital amaurosis (LCA). Fibroblasts from two unrelated clinically-identified patients (Coriell) were reprogrammed to pluripotency by retroviral transduction. These human induced Pluripotent Stem Cells (...
ORGANISM(S): Homo sapiens 
2015-01-21 | E-GEOD-43926 | biostudies-arrayexpress
GenomicsMicrobial Bile acid metabolite, 3-oxo-LCA, prohibits colorectal cancer progression
Microbial Bile acid metabolite, 3-oxo-LCA, prohibits colorectal cancer progression
PRJNA1248922 | ENA
TranscriptomicsGenome-wide analysis of mechanosensitive genes using in vivo model of mouse carotid artery endothelium exposed to disturbed flow
Recently, we have shown that disturbed flow caused by partial ligation of mouse carotid artery rapidly induces endothelial dysfunction and atherosclerosis within two weeks. To understand the molecular mechanisms by which disturbed flow induces atherosclerosis, we carried out genome-wide microarray ...
ORGANISM(S): Mus musculus 
2011-03-10 | E-GEOD-20741 | biostudies-arrayexpress
Genomics
DCA-LCA
PRJNA925821 | ENA
ProteomicsCharacterisation of the gut microbiota metaproteome in patients affected by the Williams Beuren syndrome
Analyses were performed on stool samples collected from 41 patients affected by Williams Beuren syndrome (Wills, WBSs) to evaluate their gut microbiota metaproteome signatures by LFQ and LCA approaches in comparison to 45 healthy subjects (controls, CTRs, CTRLs)
ORGANISM(S): Bacteria (ncbitaxon:2) Homo Sapiens (ncbitaxon:9606) 
2023-01-11 | MSV000091045 | MassIVE
Genomics
LCA-DCA ABX
PRJNA923748 | ENA
TranscriptomicsMicrobial Bile acid metabolite, 3-oxo-LCA, prohibits colorectal cancer progression
Objective: Bile acids (BAs) not only influence gut microbiome composition but are also metabolized by gut bacteria to form various microbial BAs. Among these, 3-oxo-lithocholic acid (-oxo-LCA) and isoalloLCA have been reported to modulate host immunity, suppress intestinal pathogens, and provide ant...
ORGANISM(S): Homo sapiens 
2025-08-14 | GSE294276 | GEO
GenomicsElucidating the molecular mechanisms underlying CRB1-related Leber congenital amaurosis (LCA)
Elucidating the molecular mechanisms underlying CRB1-related Leber congenital amaurosis (LCA)
PRJNA987610 | ENA
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