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MetabolomicsTreatment of lean and diet-induced obesity (DIO) mice with a novel stable obestatin analogue alters plasma metabolite levels as detected by untargeted LC-MS metabolomics
Introduction: Obestatin is a controversial gastrointestinal peptide purported to have metabolic actions. Objectives: This study investigated whether treatment with a stable obestatin analogue (PEG-OB(Cys10, Cys13) changed plasma metabolite levels firstly in lean and subsequently in diet-induced obes...
2017-07-25 | MTBLS334 | MetaboLights
MetabolomicsIntranasal oxytocin in lean and obese men
Not available
ORGANISM(S): Homo sapiens 
ST000770 | MetabolomicsWorkbench
MetabolomicsIWMS Study 1:Weight comparison of obese and lean patients
Not available
ORGANISM(S): Homo sapiens 
ST000106 | MetabolomicsWorkbench
TranscriptomicsLiver transcriptome comparison of divergently selected Lean and Fat mouse lines in cholesterol homeostasis, bile acids, glucose and lipoprotein metabolism
This study aimed to identify molecular basis of obesity-resistant mechanisms in the Lean line with the emphasis on lipid homeostasis. Expression profiling using custom Steroltalk v2 microarray demonstrated that Lean mice exhibit a higher hepatic expression of cholesterol synthesis genes compared to ...
ORGANISM(S): Mus musculus 
2011-10-16 | E-GEOD-24967 | biostudies-arrayexpress
MetabolomicsMetabolomic profiling of influenza: a 2009 pandemic H1N1 influenza in lean and obese mice (via tissue)
Not available
ORGANISM(S): Mus musculus 
ST000070 | MetabolomicsWorkbench
MetabolomicsMetabolomic profiling of influenza: a 2009 pandemic H1N1 influenza in lean and obese mice (via Urine)
Not available
ORGANISM(S): Mus musculus 
ST000071 | MetabolomicsWorkbench
ProteomicsClinical characterization and proteomic profiling of lean nonalcoholic fatty liver disease
To investigate the proteomic features in lean subjects with NAFLD, and to identify possible plasma proteins that provide potential application for diagnosing of NAFLD in lean individuals. Participants with or without NAFLD were divided into an overweight NAFLD group, an overweight control group, a l...
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD035514 |
TranscriptomicsTranscription profiling of human cumulus cells in vitro isolated from polycystic ovary syndrome lean and obese individuals reveals PCOS in lean and obese individuals is associated with different molecular pathways
Objective: The etiology of PCOS is mostly unknown. Existing data support both genetic and environmental factors in its pathogenesis. Design: Prospective case - control study. Setting: University Hospital. Patients: 25 patients undergoing IVF-ICSI treatment. Intervention: Genome-wide oligonucleoti...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-10946 | biostudies-arrayexpress
MetabolomicsMetabolomic profiling of influenza: a 2009 pandemic H1N1 influenza in lean and obese mice (via blood and tissue)
Not available
ORGANISM(S): Mus musculus 
ST000069 | MetabolomicsWorkbench
TranscriptomicsExpression data from liver of WNIN/Ob lean and obese rats
Obesity is risk factor for development of fatty liver. Analysis of altered gene expression gives better understading about the mechanisms involved/alterted in the development of obesity-induced fattyliver in this new obese rat model. We used Microarrays to delinate the alted gene expression in live...
ORGANISM(S): Rattus norvegicus 
2014-06-18 | E-GEOD-58576 | biostudies-arrayexpress
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