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UnknownTranscriptomic and Ultrastructural Signatures of K+-Induced Aggregation in Phytophthora parasitica Zoospores.
Not available
S-EPMC7409359 | biostudies-literature
UnknownHigh throughput error corrected Nanopore single cell transcriptome sequencing.
Not available
S-EPMC7423900 | biostudies-literature
TranscriptomicsRole of miR-125b in B-cell acute lymphoblastic leukemia (B-ALL)
B-cell acute lymphoblastic leukemia (B-ALL) is often associated with chromosomal translocations leading to the deregulation of proto-oncogenes. MicroRNAs can also be affected by chromosomal alterations and thus contribute to carcinogenesis. The microRNA miR-125b-1 is over-expressed in B-ALL cases wi...
ORGANISM(S): Mus musculus 
2012-06-20 | E-GEOD-30647 | biostudies-arrayexpress
TranscriptomicsSmall RNA next generation sequencing of mice skin biopsies from acetone-treated healthy skins and DMBA/PMA-treated hyperplastic skins, papillomas and cutaneous Squamous Cell Carcinomas
FVB/N mice were subjected to 7,12-Dimethylbenz[a]anthracene (DMBA) two-hit multistage skin carcinogenesis protocol. Mice were topically treated with 200 nmol of DMBA in 0.2 mL acetone then twice weekly for six weeks with 5 nmol PMA (Phorbol 12-myristate 13-acetate). A second hit of DMBA was performe...
ORGANISM(S): Mus musculus 
2014-02-03 | E-GEOD-52299 | biostudies-arrayexpress
TranscriptomicsEffect of mmu-miR-193b-3p and miR-365a-3p ectopic expression on the transcriptome of mouse cutaneous Squamous Cell Carcinoma cells
The mouse mSCC-20 cell line was transfected with 5nM of mmu-pre-miR-193b-3p, pre-miR-365a-3p or pre-miR-NC1. Total RNAs were extracted 30 h after transfection and hybridized on microarrays. One color experiment with 3 experimental conditions : miR-NC1- (n=4), miR-193b-3p- (n=2) and miR-365-3p- (n=2)...
ORGANISM(S): Mus musculus 
2014-02-03 | E-GEOD-52381 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of Bmi1 silenced-K562 CML cell line
The Bmi1 Polycomb protein is involved in the epigenetic repressive control of self renewal and survival of cancer initiating cells. In Chronic Myeloid Leukemia (CML), bmi1 expression increases gradually as the disease progresses from a chronic latent phase to a deadly blast crisis. We developped an ...
ORGANISM(S): Homo sapiens 
2015-05-12 | E-GEOD-54262 | biostudies-arrayexpress
TranscriptomicsRNA-SEQ on resting (R) and stimulated (S) B cells from several IgH 3'RR mutant models
We evaluated by RNA-seq obveral transcripts in B cells (resting and activated for 2 days with LPS) sorted from several KO mice models devoid of portion or all the IgH 3' Regulatory Region One RNA-seq point was realized per condition (resting or stimulated) and per genotype. Each point corresponds to...
ORGANISM(S): Mus musculus 
2016-03-02 | E-GEOD-76217 | biostudies-arrayexpress
TranscriptomicsTetraspanin CD63 acts as a pro-metastatic factor via β-catenin stabilization
The tetraspanin CD63 is implicated in pro-metastatic signaling pathways, but so far, it is unclear how CD63 levels affect the tumor cell phenotype. Here, we investigated the effect of CD63 modulation in different metastatic tumor cell lines. In vitro, knock down of CD63 induced a more epithelial-lik...
ORGANISM(S): Homo sapiens 
2015-01-23 | E-GEOD-61957 | biostudies-arrayexpress
TranscriptomicsTranscriptional signature of wounded keratinocytes reveals selective roles for ERK1/2, P38 and PI3K signalling pathways
Covering denuded dermal surface after injury requires migration, proliferation and differentiation of skin keratinocytes. To clarify the major traits controlling these intermingled biological events, we surveyed the genomic modifications occurring during the course of a scratch closure of cultured h...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-6820 | biostudies-arrayexpress
TranscriptomicsAdrenal gene expression profiles of male and female Kcnk3 null mice in basal conditions or after hormonal treatment.
Primary aldosteronism (PA) is a common form of endocrine hypertension suspected in the presence of arterial hypertension (HT), hypokalemia and low plasma renin levels. While for a long time the genetic causes of PA have remained mysterious, recent findings have revealed an important role for an alte...
ORGANISM(S): Mus musculus 
2012-08-20 | E-GEOD-37825 | biostudies-arrayexpress
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