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ProteomicsSex Impacts Cardiac Function and the Proteome Response to Thyroid Hormone in Aged Mice
Background: Sex and age have substantial influence on thyroid function. Sex influences the risk and clinical expression of thyroid disorders (TDs), with age a proposed trigger for the development of TDs. Cardiac function is affected by thyroid hormone levels with gender differences. Accordingly, we...
ORGANISM(S): Mus musculus (Mouse) 
2020-12-23 | PXD022557 | Pride
Heart Aged Thyroid hormone Lc-ms/ms 
ProteomicsIdentification of enriched O-GlcNAc proteins in hypertrophic mouse hearts
We used C57/Bl6 mice subjected to sham or transverse aortic constriction (TAC) to create pressure-overload hypertrophy (POH). From the hearts, we stabilized and labelled the O-GlcNAc moiety with tetramethylrhodamine azide (TAMRA) before enriching by TAMRA immunoprecipitation (files with "TAMRAIP"). ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-02-07 | MSV000088797 | MassIVE
ProteomicsIdentification of enriched O-GlcNAc proteins in hypertrophic and normal mouse hearts
Bottom up proteomics of O-GlcNAc antibody enriched proteins from mouse heart tissue (hypertrophic vs. normal). O-GlcNAc proteins were labeled with a click chemistry kit with the tetramethylrhodamine (TAMRA) tag, then the labeled proteins were enriched with TAMRA antibody for proteomics experiments.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-12-06 | MSV000088525 | MassIVE
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