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TranscriptomicsmicroRNA expression in human hepatitis c virus (HCV) liver biopsy samples
In order to infer the inverse expression relationships between microRNAs and mRNAs during HCV infection, we profiled both microRNA and mRNA expressions in HCV positive (HCV+) and HCV negative (HCV-) human liver biopsy tissue samples. This series includes all microRNA profiles. This series includes m...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-15288 | biostudies-arrayexpress
TranscriptomicsAcute host transcriptonal response to r1918 influenza and r1918 influenza containing the NS1 gene from A/Texas/36/91 in A549 cells
The “Spanish influenza” of 1918 claimed an unprecedented number of lives, yet the determinants of virulence for this virus are still not fully understood. Here, we used functional genomics and an in vitro human lung epithelial cell infection model to define the global host transcriptional response t...
ORGANISM(S): Homo sapiens 
2012-05-13 | E-GEOD-37951 | biostudies-arrayexpress
TranscriptomicsAcute host transcriptonal response to A/Texas/36/91 influenza and A/Texas/36/91 influenza containing the NS1 gene from r1918 in A549 cells
The M-bM-^@M-^\Spanish influenzaM-bM-^@M-^] of 1918 claimed an unprecedented number of lives, yet the determinants of virulence for this virus are still not fully understood. Here, we used functional genomics and an in vitro human lung epithelial cell infection model to define the global host transc...
ORGANISM(S): Homo sapiens 
2012-05-13 | E-GEOD-37829 | biostudies-arrayexpress
TranscriptomicsEarly transcriptional programming links progression to hepatitis C virus-induced severe liver disease in transplant patients
This study determined key transcriptional signatures associated with HCV recurrence and eventual development of severe liver disease in infected transplant patient liver biopsies over time following transplant. We identified molecular signatures associated with severe fibrosis and liver injury prior...
ORGANISM(S): Homo sapiens 
2012-02-10 | E-GEOD-34798 | biostudies-arrayexpress
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