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Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
Piwi-interacting (pi) RNAs are a class of germline-expressed small RNAs that have been linked to epigenetic programming in metazoa. C. elegans piRNAs known as 21U-RNAs are defined by more than 15,000 genome-encoded species. To explore the origin of 21U-RNAs we employed methods to enrich the 5' ends ...
ORGANISM(S): Mus musculus 
Seasonal influenza outbreaks and recurrent influenza pandemics present major challenges to public health. By studying immunological responses to influenza in different host species, it may be possible to discover common mechanisms of susceptibility in response to various influenza strains. This coul...
ORGANISM(S): Mus musculus 
A strong promoter increases transcription of the genes of interest and enhances the production of various valuable substances. For a hyperthermophilic archaeon Thermococcus onnurineus NA1, which can produce H2 by carbon monoxide oxidation, we searched for a novel endogenous strong promoter by transc...
ORGANISM(S): Thermococcus onnurineus NA1 
Total and phosphoproteomic analysis of liver and white adipose tissue from mice with specific deletion of protein kinase C epsilon in AgRP nerons of the hypothalamus, 30 min after i.p. injection with glucose.
ORGANISM(S): Mus musculus (Mouse) 
2026-02-09 | PXD065137 | Pride
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