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ProteomicsLenalidomide-induced pure red cell aplasia analysis
The RVd therapy, combining lenalidomide, bortezomib, and dexamethasone, is a mainstay treatment for multiple myeloma. A multiple myeloma patient developed pure red cell aplasia (PRCA) following RVd treatment, despite the absence of common PRCA triggers. In vitro analyses revealed lenalidomide as a p...
ORGANISM(S): Homo Sapiens 
PXD055495 |
ProteomicsBRAF inhibitors enhance erythropoiesis and treat anemia through paradoxical activation of MAPK
Erythropoiesis is a crucial part in hematopoietic system, while facing disruptions from various diseases conditions. Anemia and blood shortages has become global challenges, with current finite pharmacological options like EPO or glucocorticoids having limitations, especially in genetic anemias like...
ORGANISM(S): Homo Sapiens 
PXD055730 |
ProteomicsQuantification Quality Control Emerges as A Crucial Factor to Enhance Single Cell Proteomics Data Analysis
Mass spectrometry (MS)-based single-cell proteomics (SCP) provides us the opportunity to unbiasedly explore biological variability within cells without the limitation of antibody availability. This field is rapidly developed with the main focuses on instrument advancement, sample preparation refinem...
ORGANISM(S): Homo Sapiens (human) 
2025-01-09 | PXD048595 | JPOST Repository
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