Lee J A JA - OmicsDI

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Genomics (138)
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biostudies-arrayexpress (41)
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Technology Type

Mass Spectrometry (54)
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Liquid Chromatography MS - positive (1)
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2006 (1)
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UNIPROT ID/AC

1433B_MOUSE (2)
1433E_MOUSE (2)
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ACINU_MOUSE (2)
ACL6A_MOUSE (2)

CHEBI ID

CHEBI:16708 (9)
CHEBI:25094 (9)
CHEBI:26986 (9)
CHEBI:28300 (9)
CHEBI:30769 (9)
CHEBI:16027 (8)
CHEBI:16811 (8)
CHEBI:17568 (8)
CHEBI:17822 (8)
CHEBI:24898 (8)
CHEBI:27897 (8)
CHEBI:15428 (7)
CHEBI:16010 (7)
CHEBI:16856 (7)
CHEBI:17154 (7)
CHEBI:17368 (7)
CHEBI:18186 (7)
CHEBI:18237 (7)
CHEBI:22660 (7)
CHEBI:28044 (7)
CHEBI:15354 (6)
CHEBI:15741 (6)
CHEBI:16335 (6)
CHEBI:16449 (6)
CHEBI:18295 (6)
CHEBI:22653 (6)
CHEBI:25017 (6)
CHEBI:27266 (6)
CHEBI:27570 (6)
CHEBI:15756 (5)

Metabolite Name

Adenine (6)
Glycine (6)
Threonine (6)
Uracil (6)
AMP (5)
Glutamine (5)
Leucine (5)
Serine (5)
Valine (5)
4-Hydroxybenzaldehyde (4)
ADP (4)
ATP (4)
Alanine (4)
Aspartate (4)
Citrate (4)
Ethanolamine (4)
Glutamate (4)
Hypoxanthine (4)
Isoleucine (4)
Lactate (4)
Methionine (4)
Pantothenate (4)
Pyroglutamate (4)
Pyruvate (4)
Tryptophan (4)
Tyrosine (4)
Xanthine (4)
Acetate (3)
Adenosine (3)
Ascorbate (3)

IsPrivate

False (1)

Submitter Keywords

FROG (1)

Modelling Approach

Constraint-based model (1)

Modification

Not available (1)

Study type

Transcription profiling by array (16)
ChIP-seq (11)
RNA-seq of coding RNA (7)
Other (2)
Methylation profiling by high throughput sequencing (2)
Unknown experiment type (1)
Comparative genomic hybridization by array (1)
Genotyping by high throughput sequencing (1)

Release Date

2021 (436)
2022 (433)
2024 (407)
2023 (405)
2025 (383)
2020 (332)
2018 (262)
2019 (238)
2017 (188)
2015 (183)
2016 (177)
2014 (173)
2013 (107)
2012 (96)
2011 (80)
2010 (59)
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2009 (51)
2008 (38)
2007 (16)
2006 (9)
2004 (4)
2003 (4)
2005 (3)
2002 (1)
2001 (1)
2000 (1)
1997 (1)
1987 (1)

Lab affiliation

Department of Cell Biology, Harvard Medical School, Boston MA (3)
Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore (2)
Center for Proteomics and Metabolomics Leiden University Medical Center (1)
Center for Proteomics and Metabolomics, Leiden University Medical Center and Proteomics Centre, University of Victoria (1)
Centre for Addiction and Mental Health (1)
David Geffen School of Medicine, University of California, Los Angeles, CA 90095 Department of Molecular and Medical Pharmacology, Jonsson Comprehensive Cancer Center, Institute for Molecular Medicine, California NanoSystems Institute (1)
Department for BioMedical Research (DBMR) University of Bern Murtenstrasse 35 3008 Bern Switzerland (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA. (1)
Department of Cell Biology, Harvard Medical School, Boston, MA (1)
Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA, USA (1)
Department of Chemistry, Vanderbilt University, Nashville, TN, United States (1)
Department of Convergence Medicine, Convergence Medicine Research Center/Biomedical Research Center, Asan Medical Center, Asan Institute for Life Sciences, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea. (1)
Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390 (1)
Department of Musculoskeletal and Ageing Science Institute of Life Course and Medical Sciences University of Liverpool, UK (1)
Department of Pathology Beth Israel Deaconess Medical Center Harvard Medical School, Boston, MA, 02115, USA. (1)
Department of Pathology Cancer Center Stony Brook University (1)
Department of Pharmacology Yonsei University College of Medicine (1)
Department of Structural Biology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany (1)
Departments of Molecular Neuroscience and Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel (1)
Departments of Molecular Neuroscience and Biomolecular Sciences, Weizmann Institute of Science; Rehovot, Israel. (1)
Departments of Pathology and Microbiology & Immunology, Dalhousie University, Halifax, Canada. (1)
Departments of Pediatrics and Genetics, Stanford University, Stanford, CA, USA. (1)
Dept. Oncology Pathology, Karolinska Institutet, and ScilifeLab, Stockholm, Sweden (1)
Director of Women’s Health Research Women’s Service Line Inova Health System (1)
European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI) (1)
Finley and Gygi lab Cell Biology Department Harvard Medical School US (1)
Harvard Institutes of Medicine, BWH/Genetics 77 Avenue Louis Pasteur, Boston MA 02115, United States (1)
Head of Proteomics (1)
Icahn School of Medicine at Mount Sinai (1)

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Cwc23, an essential J-protein critical for pre-mRNA splicing with a dispensable J-domain

J-proteins are structurally diverse, obligatory co-chaperones of Hsp70s, each with a highly conserved J-domain that plays a critical role in stimulation of Hsp70â€™s ATPase activity. The essential protein, Cwc23, is one of 13 J-proteins found in the cytosol and/or nucleus of Saccharomyces cerevisiae...

ORGANISM(S): Saccharomyces cerevisiae

2010-06-21 | E-GEOD-18485 | biostudies-arrayexpress

Jasmonate-mediated stomatal closure under elevated CO2 revealed by time-resolved metabolomics

Foliar stomatal movements are critical for regulating plant water loss and gas exchange. Elevated carbon dioxide (CO2) levels are known to induce stomatal closure. However, the current knowledge on CO2 signal transduction in stomatal guard cells is limited. Here we report metabolomic responses of Br...

2017-04-25 | MTBLS312 | MetaboLights

Two Poplar-Associated Bacterial Isolates Induce Additive Favorable Responses in a Constructed Plant-Microbiome System

The biological function of the plant-microbiome system is the result of contributions from the host plant and microbiome members. The Populus root microbiome is a diverse community that has high abundance of β- and γ-Proteobacteria, both classes which include multiple plant-growth promoting represen...

2017-07-25 | MTBLS332 | MetaboLights

Biochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (NMR assay)

Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...

2019-02-07 | MTBLS640 | MetaboLights

Biochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (MS assays)

2019-02-07 | MTBLS674 | MetaboLights

Cwc23, an essential J protein critical for pre-mRNA splicing with a dispensable J domain.

Not available

S-EPMC2798280 | biostudies-literature

MetaboKit: a comprehensive data extraction tool for untargeted metabolomics (Mouse liver assays)

We have developed MetaboKit, a comprehensive software package for compound identification and relative quantification in mass spectrometry-based untargeted metabolomics analysis. In data dependent acquisition (DDA) analysis, MetaboKit constructs a customized spectral library with compound identit...

2021-11-02 | MTBLS1266 | MetaboLights

MetaboKit: a comprehensive data extraction tool for untargeted metabolomics (Standard mixture assay)

2021-11-05 | MTBLS1311 | MetaboLights

Quantitative high-throughput screening identifies cytoprotective molecules that enhance SUMO conjugation via the inhibition of SUMO-specific protease (SENP)2.