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TranscriptomicsThe two-component system ChrSA is crucial for heme tolerance and interferes with HrrSA in heme-dependent gene regulation in Corynebacterium glutamicum
We recently showed that the two-component system (TCS) HrrSA plays a central role in the control of heme homeostasis in the Gram-positive soil bacterium Corynebacterium glutamicum. Here, we characterized the function of another TCS of this organism, ChrSA, which exhibits significant sequence similar...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2012-10-31 | E-GEOD-37327 | biostudies-arrayexpress
TranscriptomicsComplex regulation of the PEP carboxykinase gene pck and characterization of its GntR-type regulator IolR as a repressor of myo-inositol utilization genes in Corynebacterium glutamicum
DNA affinity chromatography with the promoter region of the Corynebacterium glutamicum pck gene, encoding phosphoenolpyruvate carboxykinase (PEPCk), led to the isolation of four transcriptional regulators, i.e., RamA, GntR1, GntR2 and IolR. Determination of the PEPCk activity of the deletion mutant...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2013-07-29 | E-GEOD-44812 | biostudies-arrayexpress
GenomicsWhole-genome landscape of histone H2AX and M-NM-3-H2AX
Phosphorylation of the histone variant H2AX forms M-NM-3-H2AX that marks DNA double-strand break (DSB). Here we generated the sequencing-based maps of H2AX and M-NM-3-H2AX positioning in resting and proliferating cells before and after ionizing irradiation. Genome-wide locations of possible endoge...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-25577 | biostudies-arrayexpress
TranscriptomicsExpression profiles of Arabidopsis thaliana Col-0 seedlings and seedlings of a mutant impaired in cytoplasmic calcium elevation in response to cellotriose treatment (Johnson et al., 2017)
The endophytic fungus Piriformospora indica is a member of Sebacinales. It colonizes the roots of many plant species including the model plant Arabidospis thaliana (Peskan-Berghofer et al. 2004). P. indica promotes plant growth (Peskan-Berghofer et al. 2004), seed production (Shahollari et al. 2007)...
ORGANISM(S): Arabidopsis thaliana 
2018-02-09 | GSE98880 | GEO
UnknownHormone signaling linked to silkmoth sex pheromone biosynthesis involves Ca2+/calmodulin-dependent protein kinase II-mediated phosphorylation of the insect PAT family protein Bombyx mori lipid storage droplet protein-1 (BmLsd1).
Not available
S-EPMC3129191 | biostudies-literature
UnknownTetraspanin-2 promotes glucotoxic apoptosis by regulating the JNK/β-catenin signaling pathway in human pancreatic β cells.
Not available
S-EPMC5001516 | biostudies-literature
MetabolomicsJasmonate-mediated stomatal closure under elevated CO2 revealed by time-resolved metabolomics
Foliar stomatal movements are critical for regulating plant water loss and gas exchange. Elevated carbon dioxide (CO2) levels are known to induce stomatal closure. However, the current knowledge on CO2 signal transduction in stomatal guard cells is limited. Here we report metabolomic responses of Br...
2017-04-25 | MTBLS312 | MetaboLights
UnknownQuantitative high-throughput screening identifies cytoprotective molecules that enhance SUMO conjugation via the inhibition of SUMO-specific protease (SENP)2.
Not available
S-EPMC5892725 | biostudies-literature
MetabolomicsDiel metabolomics analysis of a hot spring chlorophototrophic microbial mat leads to new hypotheses of community member metabolisms
Dynamic environmental factors such as light, nutrients, salt, and temperature continuously affect chlorophototrophic microbial mats, requiring adaptive and acclimative responses to stabilize composition and function. Quantitative metabolomics analysis can provide insights into metabolite dynamics fo...
2024-02-23 | MTBLS187 | MetaboLights
UnknownTowards tunable exciton delocalization in DNA Holliday junction-templated indodicarbocyanine 5 (Cy5) dye derivative heterodimers.
Not available
S-EPMC11423794 | biostudies-literature
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