Sort   by:  
 Page size 
ProteomicsPlasma Proteome Stability at the Time of Sudden Cardiac Arrest: Implications for Biomarker Studies in Post-Resuscitation Survival
Plasma serves as a crucial source of circulating protein biomarkers for advancing resuscitation strategies in sudden cardiac arrest (SCA). However, emergency blood collection under SCA introduces preanalytical variables that may affect proteomic analyses. This study assessed plasma protein stability...
ORGANISM(S): Homo Sapiens 
2026-04-29 | PXD067885 | panorama
ProteomicsVutiglabridin ameliorates obesity by directly reducing fat mass through AMPK/lipophagy activation in adipocytes
Current anti-obesity therapies that suppress appetite often cause undesirable reductions in lean mass by indirectly depleting systemic energy store. In this study, we developed a novel anti-obesity drug, Vutiglabridin (VUTI), designed to selectively reduce fat mass while preserving lean mass. We eva...
ORGANISM(S): Mus Musculus (mouse) 
2026-04-30 | PXD069901 | JPOST Repository
ProteomicsClinical application of multiple reaction monitoring-mass spectrometry to HER2 measurements as a potential diagnostic tool for breast cancer therapy
Although the determination of HER2 expression in breast cancer would be of critical importance in the clinical management related to the selection of the patients who are expected to benefit from trastuzumab therapy, the conventional techniques have inherent limitations that disqualify their use as ...
ORGANISM(S): Homo Sapiens 
2021-03-03 | PXD017691 | panorama
ProteomicsEvaluation of nondepleted plasma multiprotein-based model for discriminating psychiatric disorders using multiple reaction monitoring-mass spectrometry: Proof of concept study
Psychiatric evaluation relies on subjective symptoms and behavioral observation, which sometimes lead to misdiagnosis. Although there have been efforts to utilize plasma proteins as objective markers, the depletion method is time-consuming. Therefore, this study aimed to enhance previous quantificat...
ORGANISM(S): Homo Sapiens 
2026-04-10 | PXD046722 | panorama
Sort   by:  
 Page size