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MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
UnknownThermodynamic mechanism for the evasion of antibody neutralization in flaviviruses.
Not available
S-EPMC4111217 | biostudies-literature
UnknownPhase II trial of cetuximab, gemcitabine, and oxaliplatin followed by chemoradiation with cetuximab for locally advanced (T4) pancreatic adenocarcinoma: correlation of Smad4(Dpc4) immunostaining with pattern of disease progression.
Not available
S-EPMC3157965 | biostudies-literature
UnknownLocus category based analysis of a large genome-wide association study of rheumatoid arthritis.
Not available
S-EPMC2935861 | biostudies-literature
UnknownPhase I Imaging and Pharmacodynamic Trial of CS-1008 in Patients With Metastatic Colorectal Cancer.
Not available
S-EPMC4881374 | biostudies-literature
TranscriptomicsTranscription profiling of human fibroblast RNA from a patient with a mitochondrial oxidative phosphorylation complex I deficiency vs normal fibroblast RNA
Comparison of fibroblast RNA from a patient with a mitochondrial oxidative phosphorylation comnplex I deficiency against normal fibroblast RNA.

Note: this experiment submission is not fully MIAME compliant, due to the unavailability of oligonucleotide sequences on the A-MEXP-70 array ("Adelai...
ORGANISM(S): Homo sapiens 
2004-09-01 | E-MEXP-119 | biostudies-arrayexpress
UnknownApproaches and outcomes of adalimumab discontinuation in patients with well-controlled inflammatory arthritis: a systematic search and review.
Not available
S-EPMC11684048 | biostudies-literature
TranscriptomicsTranscription profiling of human fibroblast RNA from patient with a mitochondrial oxidative phosphorylation complex I deficency vs normal fibroblast RNA
Comparison of fibroblast RNA from patient with a mitochondrial oxidative phosphorylation complex I deficency to normal fibroblast RNA.

Note: this experiment submission is not fully MIAME compliant, due to the unavailability of oligonucleotide sequences on the A-MEXP-70 array ("Adelaide, H.sap...
ORGANISM(S): Homo sapiens 
2004-09-01 | E-MEXP-118 | biostudies-arrayexpress
UnknownThe Influence of Race/Ethnicity and Education on Family Ratings of the Quality of Dying in the ICU.
Not available
S-EPMC4701575 | biostudies-literature
UnknownReplication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4.
Not available
S-EPMC1285162 | biostudies-literature
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