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Protein arginine deiminases (PADs) convert arginine to citrulline, altering protein structure and function. Of the five human isozymes, PAD1–4 are catalytically active with distinct tissue-specificities, yet isozyme-specific substrate recognition remains poorly defined. Here, we provide a systematic...
ORGANISM(S): Homo sapiens (Human) 
2026-04-22 | PXD071247 | Pride
This project focuses on developing highly specific monoclonal antibodies for detecting citrullinated proteins while minimizing cross-reactivity with homocitrullination. Citrullination, a post-translational modification catalyzed by PAD enzymes, plays key roles in immunity, inflammation, and disease....
ORGANISM(S): Homo sapiens (Human) 
2026-03-29 | PXD061971 | Pride
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