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Sonic hedgehog (Shh) signals via Gli transcription factors to stimulate proliferation of granule neuron precursor cells (GNPs) in the cerebellum. Deregulation of Shh target genes often results in unrestrained GNP proliferation and eventually medulloblastoma (MB), the most common pediatric brain mali...
ORGANISM(S): Mus musculus 
A copy-number variation (CNV) analysis was run on 40 CEU and YRI samples across an array set tiling across the human genome. The array contained 42 million oligos spread across 20 arrays. The final design provided 1 probe per 50bp average density across the genome.

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ORGANISM(S): Homo sapiens 
Copy-number variation (CNV) genotyping was run on 450 HapMap samples using a custom targeted array. The array contained 105 000 oligos targeted to about 10 000 CNVs.
ORGANISM(S): Homo sapiens 
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