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TranscriptomicsMolecular Remodeling of Ion Channels in Human Atrial and Ventricular Myocytes Associated with Ischemic Cardiomyopathy
Ischemic cardiomyopathy (ICM) leads to congestive heart failure and can cause sudden cardiac death due to arrhythmia. Existing molecular knowledge base of ICM is rudimentary because of lack of specific attribution to cell type and function. This study was designed to investigate cell-specific molecu...
ORGANISM(S): Homo sapiens 
2010-05-14 | E-GEOD-17294 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of feft ventricle in three genetic rat models of hypertension
Left ventricle gene expression was analyzed in three models of hypertension in order to clarify the molecular mechanisms associated with left ventricular hypertrophy. Transgenic heterozygous TGR(mRen2)27 rats, overexpressing the mouse renin gene, and their littermate negative controls, spontaneously...
ORGANISM(S): Rattus norvegicus 
2006-08-31 | E-MEXP-357 | biostudies-arrayexpress
TranscriptomicsReverse myocardial remodeling by aortic bending debanding in mice
The objective of this study was to identify alterations in gene expression during reverse myocardial remodeling in a mouse model of reversible pressure overload. Mice were subjected to 4 weeks of aortic banding (AB) or sham procedure (sAB), banding and subsequent debanding (DB3), or sham procedure a...
ORGANISM(S): Mus musculus 
2010-09-29 | E-GEOD-24454 | biostudies-arrayexpress
TranscriptomicsExpression data of Sham and post-MI myocardium from swine
The molecular mechanism underlying cardiac remodeling following myocardial infarction have been incompletely understood. Until now, most studies have been performed in rodents. We studied cardiac remodeling in the physiologically more relevant animal model, the swine. Microarray analysis was perform...
ORGANISM(S): Sus scrofa 
2011-12-21 | E-GEOD-27962 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human left ventricular apex samples
19 paired human left ventricular apex samples were harvested at the time of implant of a left ventricular assist device (PRE) and at the time of explant (POST). The cohort included patients that were clinically classified as ischemic (I) showing evidence of coronary artery disease, non-ischemic (N) ...
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-974 | biostudies-arrayexpress
GenomicsTranscriptomes of left ventricle under reverse remodeling in 4,6,8-week age mice
Transcriptomes of left ventricle under reverse remodeling in 4,6,8-week age mice
PRJNA1330224 | ENA
TranscriptomicsTranscription profiling of effect of left ventricular assist device (LVAD) support on myocardium from human congestive heart failure patients
Molecular analysis of the effect left ventricular assist device (LVAD) support has on congestive heart failure patients.
ORGANISM(S): Homo sapiens 
2007-12-13 | E-GEOD-430 | biostudies-arrayexpress
UnknownReverse Remodeling With Left Ventricular Assist Devices.
Not available
S-EPMC9132540 | biostudies-literature
GenomicsMicroRNAs associated with reverse left ventricular remodeling in humans identify pathways of heart failure progression
MicroRNAs associated with reverse left ventricular remodeling in humans identify pathways of heart failure progression
PRJNA429480 | ENA
UnknownStage-based approach to predict left ventricular reverse remodeling after mitral repair.
Not available
S-EPMC9451668 | biostudies-literature
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