Lehmann T T - OmicsDI

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Unknown (1111)
Proteomics (76)
Transcriptomics (73)
Genomics (27)
Metabolomics (15)
Models (2)
Multiomics (1)

Organisms

Homo sapiens (49)
Bombyx mori (46)
Schizosaccharomyces pombe (46)
Human immunodeficiency virus 1 (46)
Oryza sativa Indica Group (46)
Sinorhizobium meliloti BL225C (46)
Sus scrofa domesticus (46)
Ostreococcus tauri (46)
Saccharomyces cerevisiae (46)
Mycobacterium tuberculosis (13)
Mus musculus (12)
Drosophila melanogaster (9)
Danio rerio (5)
Aspergillus niger (2)
Toxoplasma gondii (2)
Mycobacterium tuberculosis H37Rv (2)
Rattus norvegicus (2)
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Mycobacterium avium subsp. paratuberculosis (1)
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Oryctolagus cuniculus (1)
Arabidopsis thaliana (1)
Mycolicibacterium smegmatis MC2 155 (1)
Escherichia coli (1)
Homo (1)
Mycolicibacterium smegmatis (1)
Human immunodeficiency virus 1 (1)
Sudan ebolavirus (1)
Ebola virus (1)

Organisms

Mus musculus (3)
Drosophila melanogaster (1)

Repository

biostudies-arrayexpress (72)
pride (46)
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Tissue

Cell culture (14)
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T cell (1)

Disease

Breast cancer (2)
Disease free (2)
Acute leukemia (2)
Mature T-cell and NK-cell lymphoma (1)
Locally advanced breast carcinoma (LABC; non-inflammatory) (1)
Lung carcinoma (1)
Focal segmental glomerulosclerosis (1)
Chronic lymphocytic leukemia (1)
Acute myeloid leukemia (1)
Alzheimer's disease (1)
Tuberculosis (1)
Amyotrophic lateral sclerosis (1)

Technology Type

Mass Spectrometry (46)
Shotgun proteomics (20)
Mass spectrometry (14)
Data-dependent acquisition (12)
Bottom-up proteomics (8)
Data-independent acquisition (3)
Affinity purification coupled with mass spectrometry proteomics (3)
SWATH MS (2)
Illumina HiSeq 2000, HumanMethylation450k Bead Chip - Genome Studio, Illumina Genome Analyzer IIx (1)
Illumina HiSeq 2000 (1)
Mass spectrometry assay (1)
Immunopeptidomics (1)
SRM/MRM (1)
Gel-based experiment (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (5)
Liquid Chromatography MS - positive - reverse phase (5)
LTQ FT (4)
Liquid Chromatography MS - negative - reverse phase (3)
NextSeq 500 (2)
Q Exactive HF (2)
Q Exactive (2)
Orbitrap Fusion Lumos (2)
LTQ Orbitrap Velos (2)
LTQ (2)
Exactive (Thermo Scientific) (2)
Liquid Chromatography MS - alternating - reverse phase (2)
Liquid Chromatography MS - positive - hilic (2)
LTQ Orbitrap XL (2)
Illumina Genome Analyzer IIx (1)
Illumina NovaSeq X (1)
Illumina HiSeq 2000 (1)
Orbitrap Eclipse (1)
Orbitrap Fusion (1)
Q Exactive Plus (1)
Orbitrap Exploris 480 (1)
QTRAP 6500 (Applied Biosystems) (1)
QTRAP 5500 (Applied Biosystems) (1)
Gas Chromatography MS - - - Liquid Chromatography MS - - - Gas Chromatography MS - positive (1)
PEGASUS HT GC-MS (LECO) (1)
Flame ionisation detector MS - (1)
Gas Chromatography MS - (1)
Liquid Chromatography MS - Positive (LC-MS (Positive)) (1)
Liquid Chromatography MS - (1)
Liquid Chromatography MS - negative - hilic (1)

Publication Date

2024 (22)
2026 (15)
2013 (14)
2012 (13)
2022 (13)
2010 (12)
2020 (9)
2011 (9)
2023 (9)
2014 (7)
2019 (6)
2017 (6)
2009 (6)
2015 (5)
2008 (5)
2021 (5)
2025 (4)
2007 (3)
2018 (3)

UNIPROT ID/AC

O53978_MYCTU (2)
DNAJ2_MYCTU (2)
I6Y498_MYCTU (2)
I6WXK4_MYCTU (2)
O06396_MYCTU (2)
Y1812_MYCTU (2)
GLPD2_MYCTU (2)
P95187_MYCTU (2)
HTDX_MYCTU (2)
P20963 (1)
Q14627 (1)
P35225 (1)
P78552 (1)
P29597 (1)
P29350 (1)
P24394 (1)
P63085 (1)
Q63844 (1)
P31938 (1)
Q63932 (1)
Q99N57 (1)
Q62245 (1)
P29351 (1)
Q62120 (1)
O14543 (1)
O60674 (1)
P07321 (1)
P14753 (1)
P42229 (1)
P51692 (1)

CHEBI ID

CHEBI:15428 (4)
CHEBI:26271 (3)
CHEBI:26986 (3)
CHEBI:15741 (3)
CHEBI:27266 (3)
CHEBI:15843 (3)
CHEBI:15756 (3)
CHEBI:83718 (2)
CHEBI:90483 (2)
CHEBI:27584 (2)
CHEBI:67042 (2)
CHEBI:28125 (2)
CHEBI:74450 (2)
CHEBI:27389 (2)
CHEBI:18346 (2)
CHEBI:83359 (2)
CHEBI:64561 (2)
CHEBI:72999 (2)
CHEBI:16450 (2)
CHEBI:17822 (2)
CHEBI:25094 (2)
CHEBI:18237 (2)
CHEBI:22660 (2)
CHEBI:22653 (2)
CHEBI:18186 (2)
CHEBI:16811 (2)
CHEBI:17234 (2)
CHEBI:28300 (2)
CHEBI:16708 (2)
CHEBI:33699 (1)

Metabolite Name

Diglycerol (2)
2-Deoxy-D-galactose (2)
D-Glyceric acid (2)
3-Hydroxypyridine (2)
Lactamide (2)
L-Allothreonine (2)
Beta-Alanine (2)
Glycerol (2)
L-Alanine (2)
Uracil (2)
Phosphate (2)
Thymine (2)
D-Arabitol (2)
6-Aminopenicillanic acid (2)
L-Proline (2)
L-Threonine (2)
4-Hydroxybenzoic acid (2)
10-Hydroxydecanoic acid (2)
Aldosterone (2)
L-Valine (2)
Methylcitrate (1)
PA(18:1(12Z)-O(9S,10R)/14:0) (1)
1,3-Propanediamine (1)
PA(20:4(8Z,11Z,14Z,17Z)/22:6(4Z,7Z,11E,13Z,15E,19Z)-2OH(10S,17)) (1)
PA(TXB2/18:1(11Z)) (1)
2-Isopropoxyethanol (1)
6-Amino-2-methyl-2H-1,3-benzoxazin-4(3H)-one (1)
PS(18:1(9Z)/18:1(12Z)-O(9S,10R)) (1)
Alpha-Fluoromethylhistamine (1)
2-(4-(2-Carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine (1)

IsPrivate

False (2)

First Public Date

2022 (2)
2019 (1)
2014 (1)

Modelling Approach

Ordinary differential equation model (2)

Study type

Transcription profiling by array (52)
RNA-seq of coding RNA (6)
Methylation profiling by array (5)
Other (2)
ChIP-seq (2)
RNA-seq of total RNA (2)
Transcription profiling by tiling array (1)
Comparative genomic hybridization by array (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2023 (134)
2021 (126)
2022 (123)
2024 (118)
2025 (104)
2020 (96)
2018 (72)
2019 (61)
2017 (61)
2016 (40)
2014 (38)
2013 (33)
2015 (32)
2026 (28)
2012 (27)
2010 (24)
2011 (21)
2008 (15)
2009 (11)
2007 (5)
2002 (5)
2003 (4)
2006 (2)
2005 (2)
2000 (1)

Lab affiliation

Department of Oncology-Pathology, Karolinska Institutet, 171 77 Stockholm, Sweden Institute of Molecular and Cell Biology, A*STAR, Singapore 138673, Singapore (6)
Department of Oncology-Pathology, Karolinska Institutet, 171 77 Stockholm, Sweden Institute of Molecular and Cell Biology, A*STAR, Singapore 138673, Singapore (2)
Ludwig-Maximilians-Universität München Genzentrum Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 D-81377 München (2)
Department of Oncology-Pathology, Karolinska Institutet and Science for Life Laboratory (lab head) (1)
Otto von Guericke University, Bioprocess Engineering, Universitätsplatz 2, 39106 Magdeburg, Germany (1)
Otto-von-Guericke University Magdeburg (1)
TU München Institut für Chemie Organische Chemie II Lichtenbergstr. 4 85747 Garching (1)
Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charite ‐ Universitatsmedizin, Germany; German Center for Lung Research (DZL), Associated Partner Site, Germany; Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Germa (1)
Canadian Blood Services, Centre for Innovation, Ottawa, Ontario, Canada; Biochemistry, Microbiology and Immunology department, University of Ottawa, Ottawa, Canada. (1)
Clinical Proteomic Platform CHU de Montpellier - Hôpital St. Eloi Institute of Regenerative Medicine - Biotherapy - IRMB 80, av A. Fliche, 34295 Montpellier Cedex 5 (1)
Otto von Guericke Universität Magdeburg (1)
Department of Preclinical Development and Validation, Fraunhofer Institut for Cell Therapy and Immunology IZI, Leipzig, Germany (1)
Biozentrum der LMU München Pflanzenwissenschaften Großhaderner Str. 2-4 82152 Planegg-Martinsried (1)
Department of Oncology-Pathology, Karolinska Institutet, 171 77 Stockholm, Sweden Institute of Molecular and Cell Biology, A*STAR, Singapore 138673, Singapor (1)
MSAP USR 3290 CNRS Cité scientifique Villeneuve d'Ascq France (1)
Department of Biochemistry & Molecular Biology Michigan State University East Lansing, MI 48824 USA (1)
Mikrobielle Proteomik, Helmholtz-Zentrum für Infektionsforschung, Braunschweig, Germany (1)
1Institute of Lung Health and Immunity, Comprehensive Pneumology Center Munich with the CPC-M bioArchive, Helmholtz Center Munich, Research Center for Environmental Health, Member of the German Center of Lung Research (DZL), Germany (1)
Department of Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology and BIOSS Centre for Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany (1)
Systems Biology of Signal Transduction, German Cancer Research Center Heidelberg, Germany (1)
Department of Molecular Systems Biology, Microbiome biology Group, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany (1)
CPRO, Helmholtz-Zentrum für Infektionsforschung, Braunschweig, Germany (1)
Biozentrum der LMU München Pflanzenwissenschaften Großhaderner Str. 2-4 82152 Planegg-Martinsried Germany (1)
Section eScience (S.3), Federal Institute for Materials Research and Testing, Berlin, Germany Bioinformatics Unit (MF1), Department for Methods Development and Research Infrastructure, Robert Koch Institute, Berlin, Germany (1)
Clinic of Reproductive Medicine, Department of Farm Animals Vetsuisse-Faculty University Zurich (1)
ZIK Septomics, University Hospital Jena, Germany (1)
Department of Neurology, Faculty of Medicine, University of Cologne and University Hospital Cologne, Kerpener Strasse 62, 50937 Cologne, Germany (1)
Department Molekulare Systembiologie Helmholtz-Zentrum für Umweltforschung GmbH - UFZ Permoserstraße 15 | 04318 Leipzig (1)
Helmholtz-Centre for Environmental Research - UFZ GmbH Department of Molecular Toxicology Permoserstrasse 15, 04318 Leipzig, Germany (1)
Cell biology of neurodegenerative diseases Institute of Anatomy and Cell Biology Ulm University Ulm Germany (1)

Tags

xref:PubMed:35477759 (2)
xref:PubMed:31395598 (1)
xref:PubMed:25104425 (1)

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Mycobacterium tuberculosis-derived linoleic acid increases regulatory T cell function to promote bacterial survival within macrophages

Regulatory T cells (Tregs) expand during Mycobacterium tuberculosis (Mtb) infection and suppress T cell mediated control. Whether Mtb actively contributes to this process is unclear. Here, using a genome-wide mutant library, we show that expression of Mtb Rv1272c, an ATP-binding cassette transpor...

2025-09-28 | MTBLS12875 | MetaboLights

HiRIEF-LC-MS based proteomics analysis of subcellular fractions of human CD4+ T-Cells with and without T-cell Receptor stimulation.

Subcellular proteomics analysis of human T-cells in response to T-cell receptor stimulation. High Resolution Isoelectric Focusing (HiRIEF) LC-MS/MS and relative quantification by TMT 10-plex was used to analyze subcellular fractions (Cytosol, Nuclear and Mitochondria-Small Organelle-Membrane) of Hum...

ORGANISM(S): Homo sapiens (Human)

2019-11-13 | PXD013284 | Pride

Single-cell transcriptome and T cell receptor profiling of the tuberculin skin test

We undertook single cell RNA, TCR and antibody-derived tag (ADT) sequencing of human skin suction blisters induced at the site of of the tuberculin skin test on day 2. This submission comprises data from 31 individuals (9 male, 22 female) with immunological memory to mycobacterial antigens. TotalSeq...

ORGANISM(S): Homo sapiens

2026-07-09 | E-MTAB-14246 | biostudies-arrayexpress

T-cell acute lymphoblastic leukemia in association with Borjeson-Forssman-Lehmann syndrome due to a mutation in PHF6.

Not available

S-EPMC2933084 | biostudies-literature

Bulk RNA sequencing of day 2 and day 7 biopsies from the tuberculin skin test in people with latent tuberculosis

We used the tuberculin skin test (TST) as human challenge model to study the temporal evolution of the immune response to Mycobacterium tuberculosis (Mtb) antigens in vivo. Study participants comprised healthy HIV seronegative adults, 18-60 years of age. Latent tuberculosis (TB) infection was define...

ORGANISM(S): Homo sapiens

2025-12-18 | E-MTAB-14687 | biostudies-arrayexpress

Structural and functional insights into the human Borjeson-Forssman-Lehmann syndrome-associated protein PHF6.

Not available

S-EPMC3974978 | biostudies-literature

Borjeson-Forssman-Lehmann syndrome: A case report.

Not available

S-EPMC10930350 | biostudies-literature

Discordance Between the Predicted Versus the Actually Recognized CD8+ T Cell Epitopes of HCMV pp65 Antigen and Aleatory Epitope Dominance.

Not available

S-EPMC7900545 | biostudies-literature

CERI, CEFX, and CPI: Largely Improved Positive Controls for Testing Antigen-Specific T Cell Function in PBMC Compared to CEF.