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MetabolomicsA Novel Approach to Characterize the Lipidome of Marine Archaeon Nitrosopumilus maritimus by Ion Mobility Mass Spectrometry

Archaea are differentiated from the other two domains of life by their biomolecular characteristics. One such characteristic is the unique structure and composition of their lipids. Characterization of the whole set of lipids in a biological system (the lipidome) remains technologically challengi...

2021-12-16 | MTBLS3714 | MetaboLights
GenomicsChIP-seq of WT(with 35S-SUC2 transgene) and proMBD7::gMBD7:4xMYC transgenic plants
In eukaryotes, heterochromatin is characterized by numerous epigenetic marks, including DNA methylation. Spreading of these marks into nearby active genes must be avoided in order to maintain appropriate gene expression. Here, we uncover Arabidopsis Methyl-CpG-Binding Domain 7 (MBD7) and Increased D...
ORGANISM(S): Arabidopsis thaliana 
2015-01-29 | E-GEOD-58789 | biostudies-arrayexpress
ProteomicsProteomic Screening of OLP/OLL-EVs
In this project, we first screened proteomics of OLP/OLL tissue-derived extracellular vesiclesEVs
ORGANISM(S): Homo Sapiens 
2021-06-25 | PXD026938 |
GenomicsMethlyC-Seq of ibm1-4
Using MethylC-Seq to provide single-base resulution of DNA methylation status in ibm1-4 mutant 1 sample examined, ibm1-4 mutant
ORGANISM(S): Arabidopsis thaliana 
2013-09-06 | E-GEOD-48053 | biostudies-arrayexpress
TranscriptomicsmRNA-Seq of asi1-1, wild-type and MethlyC-Seq of asi1-1
1, Using mRNA-Seq to get expression profiling of asi1-1 mutant and WT; 2, Using MethylC-Seq to provide single-base resulution of DNA methylation status in asi1-1 mutant mRNA-Seq: 2 samples examined, Col-0 wild-type with 35S-SUC2 transgene(termed as WT) and asi1-1 mutant (Col-0 background with 35S-SU...
ORGANISM(S): Arabidopsis thaliana 
2013-09-06 | E-GEOD-48026 | biostudies-arrayexpress
ProteomicsSILAC-based quantitative mass spectrometry analysis of RPA1-containing protein complex
SILAC-based quantitative mass spectrometry analysis of RPA1-containing protein complex
ORGANISM(S): Homo Sapiens 
2021-08-25 | PXD028105 |
TranscriptomicsRNA-seq of retinal organoids derived from RPGR patient-, control- and mutation-corrected-iPSC at different developmental stages
Retinitis pigmentosa (RP) is an irreversible and inherited retinopathy. RPGR mutations are the most common causes of this disease. It remains challenging to decipher the mechanism of RPGR mutation because of the lack of appropriate study models. The substitution of patient-specific diseased retina w...
ORGANISM(S): Homo sapiens 
2020-02-01 | E-MTAB-6490 | biostudies-arrayexpress
ProteomicsA proteomic investigation of the dorsal muscle in Tibetan sheep
Firstly, the back muscle samples of Tibetan sheep of the same age were collected for subsequent proteomic analysis. The integrated and analyzed results aimed to identify proteins and pathways associated with meat quality and growth regulation in sheep, thereby providing a theoretical foundation for...
ORGANISM(S): Ovis Aries 
2024-07-26 | PXD054235 |
MetabolomicsMitochondrial Transplantation Ameliorates Doxorubicin-Induced Cardiac Dysfunction via Activating Glutamine Metabolism
Doxorubicin is a wildly used effective anticancer agent. However, doxorubicin use is also related to cardiotoxic side effect in some patients. Mitochondrial damage has been shown to be one of the pathogeneses of doxorubicin-induced myocardial injury. In this study, we test the hypothesis that mitoch...
2025-03-13 | MTBLS7989 | MetaboLights
TranscriptomicsMultiple Salivary Biomarkers for Early Detection of Pancreatic Cancer
Pancreatic cancer is the fourth leading cause of cancer death. Lack of early detection technology for pancreatic cancer invariably leads to a typical clinical presentation of incurable disease at initial diagnosis. Oral fluid (saliva) meets the demand for non-invasive, accessible, and highly efficie...
ORGANISM(S): Homo sapiens 
2008-12-30 | E-GEOD-14245 | biostudies-arrayexpress
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