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Monomeric C-reactive protein (mCRP) plays a role in cerebrovascular damage mediated by apolipoprotein E4 (ApoE4) in Alzheimer's disease (AD) pathogenesis. Using proteomic profilings, we found altered cytoskeleton proteins in the microvasculature of AD brains, including increased levels of hyperphosp...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-05-06 | PXD051529 | Pride
Newcastle disease (ND) is an acute, febrile, and highly contagious disease caused by the virulent Newcastle disease virus (vNDV) worldwide. The disease causes serious economic losses to the poultry industry. However, the metabolic changes caused by vNDV infection remain unclear. The objective of thi...
2019-12-20 | MTBLS1115 | MetaboLights
Alkaline salts (e.g., NaHCO3 and Na2CO3) causes more severe morphological and physiological damage to plants than neutral salts (e.g., NaCl and Na2SO4) due to differences in pH. The mechanism by which plants respond to alkali stress is not fully understood, especially in plants having symbotic relat...
2018-07-27 | MTBLS481 | MetaboLights
Neutropenia is a common complication in the treatment of hematological diseases and the most common predisposing factor for invasion by fungi, such as Candida krusei. Recent studies have shown that C. krusei, a life-threatening pathogen, has developed resistance to amphotericin B (AMB). However, the...
ORGANISM(S): Pichia Kudriavzevii 
2023-02-09 | PXD039973 |
Agrobacterium tumefaciens-mediated genetic transformation has been routinely used in rice for more than a decade. However, the transformation efficiency of the indica rice variety is still unsatisfactory and much lower than that of japonica cultivars. Further improvement on the transformation effici...
ORGANISM(S): Oryza sativa Japonica Group 
To clarify the effect of Mitf mutation on stria vascularis transcriptome and identify downstream-genes of Mitf pathway which responsible for hearing development, we employed high-throughput sequencing to analyze the transcriptome of MitfR/r and Mitfr/r stria vascularis. Compare the transcriptome dif...
ORGANISM(S): Sus scrofa 
islation of AD mitochondrial and then detect the changes
ORGANISM(S): Mus Musculus 
2022-04-03 | PXD032992 |
TMT-based quantitative proteomic analysis of YexiangB and the OsMKK3 mutant line to obtain regulated proteins
ORGANISM(S): Oryza Sativa 
2022-11-09 | PXD038056 |
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