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ProteomicsMyocardial recovery with mechanical circulatory support is linked to alternative splicing and subcellular localization of CAMK2D
Cardiac reverse remodeling occurs in a small subset of heart failure patients treated with guideline-directed therapies. This phenomenon, which is defined by reduced ventricular dilatation and improved systolic function, is most common in patients receiving left ventricular assist device (LVAD) ther...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD068397 | Pride
Lvad proteomics 
ProteomicsMyocardial recovery with mechanical circulatory support is linked to alternative splicing and subcellular localization of CAMK2D
Cardiac reverse remodeling occurs in a small subset of heart failure patients treated with guideline-directed therapies. This phenomenon, which is defined by reduced ventricular dilatation and improved systolic function, is most common in patients receiving left ventricular assist device (LVAD) ther...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-01-12 | PXD068395 | Pride
Lvad phospho-proteomics 
ProteomicsMyocardial recovery with mechanical circulatory support is linked to alternative splicing and subcellular localization of CAMK2D
Cardiac reverse remodeling occurs in a small subset of heart failure patients treated with guideline-directed therapies. This phenomenon, which is defined by reduced ventricular dilatation and improved systolic function, is most common in patients receiving left ventricular assist device (LVAD) ther...
ORGANISM(S): Homo sapiens (Human) 
2026-01-12 | PXD068672 | Pride
Human lvad phospho-proteomics 
TranscriptomicsComparison of exercise and pregnancy-induced cardiac hypertrophy
Comparative analysis of mouse cardiac left ventricle gene expression: voluntary wheel exercise and pregnancy-induced cardiac hypertrophy We performed microarray analysis on RNA from left ventricles of mice in non-pregnant diestrus cycle, mid-pregnancy (MP), late-pregnancy (LP), and immediate post-pa...
ORGANISM(S): Mus musculus 
2012-03-08 | E-GEOD-36330 | biostudies-arrayexpress
TranscriptomicsGenome-wide transcript profiling for native porcine valvular interstitial cells and those cultured on TCPS and treated with TGF-β1
Fibrotic diseases have significant health impact and have been associated with differentiation of the resident fibroblasts into myofibroblasts. In particular, stiffened extracellular matrix and TGF-β1 in fibrotic lesions have been shown to promote pathogenic myofibroblast activation and progression ...
ORGANISM(S): Sus scrofa 
2013-09-02 | E-GEOD-48839 | biostudies-arrayexpress
ProteomicsLongevity of cardiac and skeletal muscle proteins in MYH7 transgenic mice
Mice with transgenic expression of MYH7 with a myc-tag at the C-terminus generated in the Leinwand lab were analyzed. The transgene is expressed under control of a skeletal muscle specific MCK promoter, as previously described in: https://pmc.ncbi.nlm.nih.gov/articles/PMC11060730/ Mice were injecte...
ORGANISM(S): Mus Musculus (mouse) 
2026-04-26 | PXD064177 | JPOST Repository
TranscriptomicsComparative analysis of mouse cardiac gene expression: diet, sex, and disease
The perception that soy food products and dietary supplements will have beneficial effects on heart health has led to a massive consumer market. However, we have previously noted that diet has a profound effect on disease progression in a genetic model of hypertrophic cardiomyopathy (HCM). In this m...
ORGANISM(S): Mus musculus 
2010-12-01 | E-GEOD-25700 | biostudies-arrayexpress
ProteomicsLongevity of cardiac and skeletal muscle proteins
Mice were injected with two 500μL injections of 0.15M NaCl dissolved in 99.9% D2O, separated by a four-hour interval. Then, the mice were given ad libitum access to 8% D2O drinking water for the remainder of the experiment. Mice were euthanized and dissected on days 0, 1, 2, 3, 4, 6, 8, 10, 15, 20, ...
ORGANISM(S): Mus Musculus (mouse) 
2026-04-26 | PXD063579 | JPOST Repository
TranscriptomicsThe impact of a phytoestrogen-rich diet on cardiac gene expression in the context of HCM
A soy diet worsens the progression of an inherited form of hypertrophic cardiomyopathy (HCM) in male mice when compared to casein-fed mice. Females are largely resistant to this diet effect and better preserve cardiac function. We hypothesized that the abundant phytoestrogens found in soy are mainly...
ORGANISM(S): Mus musculus 
2011-06-02 | E-GEOD-29648 | biostudies-arrayexpress
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