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UnknownBioorthogonal click labeling of an amber-free HIV-1 provirus for in-virus single molecule imaging.
Structural dynamics of human immunodeficiency virus 1 (HIV-1) envelope (Env) glycoprotein mediate cell entry and facilitate immune evasion. Single-molecule FRET using peptides for Env labeling revealed structural dynamics of Env, but peptide use risks potential effects on structural integrity/dynami...
S-EPMC10960674 | biostudies-literature
UnknownCUX1-related neurodevelopmental disorder: deep insights into phenotype-genotype spectrum and underlying pathology.
Heterozygous, pathogenic CUX1 variants are associated with global developmental delay or intellectual disability. This study delineates the clinical presentation in an extended cohort and investigates the molecular mechanism underlying the disorder in a Cux1+/- mouse model. Through intern...
S-EPMC10620399 | biostudies-literature
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