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TranscriptomicsComparison of gene expression profile in embryonic mesencephalon and neuronal primary cultures
In the mammalian central nervous system (CNS) an important contingent of dopaminergic neurons are localized in the substantia nigra and in the ventral tegmental area of the ventral midbrain. They constitute an anatomically and functionally heterogeneous group of cells involved in a variety of regula...
ORGANISM(S): Rattus norvegicus 
2009-05-10 | E-GEOD-15920 | biostudies-arrayexpress
TranscriptomicsRapid conversion of fibroblasts into functional forebrain GABAergic interneurons by direct genetic reprogramming
Transplantation of GABAergic interneurons (INs) can sustain long-standing benefits in animal models of epilepsy and other neurological disorders. In a therapeutic perspective, a renewable source of functional GABAergic INs is needed. Here, we identified five factors (Foxg1, Sox2, Ascl1, Dlx5 and Lhx...
ORGANISM(S): Mus musculus 
2015-12-15 | E-GEOD-74065 | biostudies-arrayexpress
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