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ProteomicsDetecting single amino acids and small peptides by combining isobaric tags and peptidomics
Single amino acids and small endogenous peptides play important roles in maintaining a properly functioning organism. These molecules are however currently only routinely identified in targeted approaches. In a small proof-of-concept mass spectrometry experiment we found that by combining isobaric t...
ORGANISM(S): Homo sapiens (Human) 
2019-06-26 | PXD012872 | Pride
Cerebrospinal fluid Tmt Isobaric peptidomics Peptidomics Tandem mass tag 
ProteomicsParallel reaction monitoring assay development for multiple sclerosis biomarkers in cerebrospinal fluid.
We have developed and tested parallel reaction monitoring (PRM) assays for 25 proteins highly relevant as cerebrospinal fluid (CSF) biomarkers for multiple sclerosis, representing various biological processes affected in the disease. The proteins were represented by 72 peptides selected according to...
ORGANISM(S): Homo Sapiens Rattus Norvegicus 
2021-05-20 | PXD017281 | panorama
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