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GenomicsMassive Genomic Rearrangment Acquired in a Single Catastrophic Event During Cancer Development
Cancer is driven by mutation. Using Agilent exome hybridisation capture and Illumina GA massively parallel sequencing technology, we aim to sequence ~1600 microRNAs plus the protein coding genome of 25 matched human renal cancer samples. Bespoke algorithms are being developed to identify the somatic...
EGAS00000000029 | EGA
GenomicsEGAD00000000052
Sequencing data from natching Pancreatic Carcinoma samples
EGAD00000000052 | EGA
GenomicsThe patterns and dynamics of genomic instability in metastatic pancreatic cancer
Pancreatic cancer is an aggressive malignancy with a five-year mortality of 97–98%, usually due to widespread metastatic disease. Previous studies indicate that this disease has a complex genomic landscape, with frequent copy number changes and point mutations, but genomic rearrangements have not ...
EGAS00000000064 | EGA
GenomicsMassive genomic rearrangement acquired in a single catastrophic event during cancer development - samples
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
EGAD00001000002 | EGA
TranscriptomicsThe 'PUCE CAFÉ' project: A genome-wide 15K coffee microarray, a new tool to discover candidate genes correlated to quality traits
Background: Understanding the genetic elements that contribute to key aspects of coffee biology will impact future agronomical improvements for this economically important tree. The past years, EST collections were generated in Coffee, opening the possibility to create new tools for functional genom...
ORGANISM(S): Coffea arabica 
2011-11-01 | E-GEOD-24754 | biostudies-arrayexpress
TranscriptomicsGermline duplication of ATG2B and GSKIP predisposes to familial essential thrombocythemia rapidly progressing to acute leukemia
No major predisposing gene for familial myeloproliferative neoplasms (MPN) has been identified. Here, we demonstrate that the autosomal dominant transmission of a 700 kb duplication in four geographically-related families predisposes to MPN rapidly progressing to acute leukemia. Using induced plurip...
ORGANISM(S): Homo sapiens 
2015-08-05 | E-GEOD-67938 | biostudies-arrayexpress
UnknownIntegrating artificial intelligence into lung cancer screening: a randomised controlled trial protocol.
Not available
S-EPMC10868245 | biostudies-literature
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