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ProteomicsUBQLN2 restrains the domesticated retrotransposon PEG10 to maintain neuronal health in ALS
Amyotrophic Lateral Sclerosis (ALS) is a rare neurodegenerative disease characterized by motor neuron dysfunction and loss, leading to progressive paralysis and death. A portion of ALS cases is caused by mutation of the proteasome shuttle factor Ubiquilin 2 (UBQLN2), but the molecular pathway leadin...
ORGANISM(S): Homo sapiens (Human) 
2023-03-24 | PXD031964 | Pride
Q-exactive hf-x Tmt Als Human spinal cord 
ProteomicsSimple, single-shot phosphoproteomic analysis of heat-stable tau
We developed a simple, antibody-free approach for single shot analysis of tau phosphorylation across the entire protein by liquid-chromatography tandem mass spectrometry (LC-MS/MS) to study age-related changes in tau phosphorylation. This methodology is species independent; thus, while initially dev...
ORGANISM(S): Rattus norvegicus (Rat) Macaca mulatta (Rhesus macaque) 
2021-11-25 | PXD027971 | Pride
Phosphoproteomics Brain Tau Heat-stable 
UnknownEffect of Hydroxychloroquine in Hospitalized Patients with Covid-19.
Not available
S-EPMC7556338 | biostudies-literature
UnknownDexamethasone in Hospitalized Patients with Covid-19.
Not available
S-EPMC7383595 | biostudies-literature
UnknownAzithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC7884931 | biostudies-literature
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