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ProteomicsApoptotic priming in senescence predicts selective senolysis by quantitative analysis of mitochondrial dependencies
Cellular senescence contributes to a variety of pathologies associated with aging and is implicated as a cellular state in which cancer cells can survive treatment. Reported senolytic drug treatments act through varying molecular mechanisms, but heterogeneous efficacy across the diverse contexts of ...
ORGANISM(S): Homo sapiens (Human) 
2024-12-17 | PXD054626 | Pride
Cellular senescence Navitoclax (abt263) 
GenomicsWhole Genome and Exon Capture Sequencing of Bladder Cancers

One primary bladder cancer and paired peripheral blood sample were subjected to whole genome sequencing on an Illumina HiSeq 2000 platform. This technology was utilized to investigate the genetic basis of a durable remission of metastatic bladder cancer in a patient treated with everolimus, a dru...

phs000535.v1.p1 | EGA
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