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MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
MetabolomicsIntegrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE‐mediated pediatric cow's milk allergy

BACKGROUND: IgE-mediated cow's milk allergy (IgE-CMA) is one of the first allergies to arise in early childhood and may result from exposure to various milk allergens, of which β-lactoglobulin (BLG) and casein are the most important. Understanding the underlying mechanisms behin...

2024-02-15 | MTBLS6768 | MetaboLights
ProteomicsTHEM6-mediated lipid remodelling sustains stress resistance in cancer (Part1 : AP-MS)
Despite the clinical benefit of androgen-deprivation therapy (ADT), the majority of patients with advanced prostate cancer (PCa) ultimately develop lethal castration-resistant prostate cancer (CRPC). In this study, we identified thioesterase superfamily member 6 (THEM6) as a marker of ADT resistance...
ORGANISM(S): Homo sapiens (Human) 
2021-12-11 | PXD024407 | Pride
Castration-resistant prostate cancer Cancer metabolism Endoplasmic reticulum Cancer proteomics 
UnknownAutoimmunity affecting the biliary tract fuels the immunosurveillance of cholangiocarcinoma.
Not available
S-EPMC8429038 | biostudies-literature
UnknownCCDC88B is required for pathogenesis of inflammatory bowel disease.
Not available
S-EPMC5640600 | biostudies-literature
UnknownInterferon-γ and proliferation responses to Salmonella enterica Serotype Typhi proteins in patients with S. Typhi Bacteremia in Dhaka, Bangladesh.
Not available
S-EPMC3110156 | biostudies-literature
UnknownThe risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.
Not available
S-EPMC9173764 | biostudies-literature
UnknownScalable production and immunogenicity of a cholera conjugate vaccine.
Not available
S-EPMC8609181 | biostudies-literature
TranscriptomicsA Supervised Risk Predictor of Breast Cancer Based on Biological Subtypes
Purpose: The biological subtypes of breast cancer designated as Luminal A, Luminal B, HER2+/ER-, and Basal-like are clinically important for prognosis and planning treatment strategies. Recognizing that there is a continuum in both the spectrum of breast cancer disease and the risk of survival, we s...
ORGANISM(S): Homo sapiens 
2010-06-24 | E-GEOD-10886 | biostudies-arrayexpress
UnknownComparative effectiveness of immediate antiretroviral therapy versus CD4-based initiation in HIV-positive individuals in high-income countries: observational cohort study.
Not available
S-EPMC4643831 | biostudies-literature
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